Cover Picture: BF₃·Et₂O Promoted Sulfuration of Steroidal Sapogenins (Chin. J. Chem. 6/2015)

Jun Wang,

Corresponding Author

Jun Wang

[email protected]

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Department of Chemistry, South University of Science and Technology, Shenzhen, Guangdong 518055, China

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China, Tel.: 0086-0755-88018317; Fax: 0086-0755-88018304Search for more papers by this author

Jingjing Wu,

Jingjing Wu

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Search for more papers by this author

Weisheng Tian,

Corresponding Author

Weisheng Tian

[email protected]

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China, Tel.: 0086-0755-88018317; Fax: 0086-0755-88018304Search for more papers by this author

Jun Wang,

Corresponding Author

Jun Wang

[email protected]

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Department of Chemistry, South University of Science and Technology, Shenzhen, Guangdong 518055, China

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China, Tel.: 0086-0755-88018317; Fax: 0086-0755-88018304Search for more papers by this author

Jingjing Wu,

Jingjing Wu

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Search for more papers by this author

Weisheng Tian,

Corresponding Author

Weisheng Tian

[email protected]

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China, Tel.: 0086-0755-88018317; Fax: 0086-0755-88018304Search for more papers by this author

First published: 17 June 2015

https://doi.org/10.1002/cjoc.201590013

Citations: 1

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Graphical Abstract

The cover picture shows a direct synthesis of 26-thio steroidal sapogenins from natural steroidal sapogenins, which serve as an important kind of resource compounds and basic starting materials in steroidal pharmaceutical industry. This method was based on a key and magic BF₃·Et₂O promoted C-26 sulfuration of steroidal sapogenins, which resulted in the direct replacement of the oxygen atom in F-ring of steroidal sapogenins by sulfur. The synthesis not only provides a concise method for 26-thio steroidal sapogenins, but also presents an ideal model of the utilization of steroidal sapogenins. More details are discussed in the article by Wang and Tian et al. on page 632–636.