Cover
Free Access
Inside Cover: pH-Responsive Protein Conformation Transistor (Angew. Chem. Int. Ed. 1/2024)
First published: 23 November 2023
Graphical Abstract
The successful creation of “core–shell” protein nanocrystals, which demonstrate ultra-rapid crystalline cross-linking behavior at pH levels above 7.6, underpins the concept of a protein conformation proton transistor. As reported by Peng Yang et al. in their Communication (e202310879), this pH-triggered cross-linking can be feasibly accomplished under conditions that resemble physiological environments, highlighting its significant potential in biomedicine, biosensing, and microfluidic chemistry.
