Volume 52, Issue 27 p. 7044
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Back Cover: Mix to Validate: A Facile, Reversible PEGylation for Fast Screening of Potential Therapeutic Proteins In Vivo (Angew. Chem. Int. Ed. 27/2013)

Dr. Tae Hyung Kim

Dr. Tae Hyung Kim

Russell H. Morgan Department of Radiology and Radiological Science, Center for Cancer Nanotechnology Excellence, Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University, 400 North Broadway, Baltimore, MD 21231 (USA)

College of Pharmacy, Sungkyunkwan University, 300 Chonchon-dong, Jangan-gu, Suwon 440-746 (Korea)

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Dr. Magdalena Swierczewska

Dr. Magdalena Swierczewska

Institute for NanoBioTechnology, Russell H. Morgan Department of Radiology and Radiological Science, Center for Cancer Nanotechnology Excellence, Johns Hopkins University (USA)

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Dr. Yumin Oh

Dr. Yumin Oh

Russell H. Morgan Department of Radiology and Radiological Science, Center for Cancer Nanotechnology Excellence, Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University, 400 North Broadway, Baltimore, MD 21231 (USA)

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Dr. AeRyon Kim

Dr. AeRyon Kim

Department of Pathology, Johns Hopkins University (USA)

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Prof. Dr. Dong Gyu Jo

Prof. Dr. Dong Gyu Jo

College of Pharmacy, Sungkyunkwan University, 300 Chonchon-dong, Jangan-gu, Suwon 440-746 (Korea)

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Prof. Dr. Jae Hyung Park

Prof. Dr. Jae Hyung Park

Department of Polymer Science and Engineering, Sungkyunkwan University, Suwon (Korea)

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Prof. Dr. Youngro Byun

Prof. Dr. Youngro Byun

College of Pharmacy, Seoul National University, Seoul (Korea)

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Prof. Dr. Scheherazade Sadegh-Nasseri

Prof. Dr. Scheherazade Sadegh-Nasseri

Department of Pathology, Johns Hopkins University (USA)

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Prof. Dr. Martin G. Pomper

Prof. Dr. Martin G. Pomper

Institute for NanoBioTechnology, Russell H. Morgan Department of Radiology and Radiological Science, Center for Cancer Nanotechnology Excellence, Johns Hopkins University (USA)

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Prof. Dr. Kang Choon Lee

Corresponding Author

Prof. Dr. Kang Choon Lee

College of Pharmacy, Sungkyunkwan University, 300 Chonchon-dong, Jangan-gu, Suwon 440-746 (Korea)

Kang Choon Lee, College of Pharmacy, Sungkyunkwan University, 300 Chonchon-dong, Jangan-gu, Suwon 440-746 (Korea)

Seulki Lee, Russell H. Morgan Department of Radiology and Radiological Science, Center for Cancer Nanotechnology Excellence, Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University, 400 North Broadway, Baltimore, MD 21231 (USA)

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Prof. Dr. Seulki Lee

Corresponding Author

Prof. Dr. Seulki Lee

Russell H. Morgan Department of Radiology and Radiological Science, Center for Cancer Nanotechnology Excellence, Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University, 400 North Broadway, Baltimore, MD 21231 (USA)

Kang Choon Lee, College of Pharmacy, Sungkyunkwan University, 300 Chonchon-dong, Jangan-gu, Suwon 440-746 (Korea)

Seulki Lee, Russell H. Morgan Department of Radiology and Radiological Science, Center for Cancer Nanotechnology Excellence, Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University, 400 North Broadway, Baltimore, MD 21231 (USA)

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First published: 06 June 2013

Graphical Abstract

Increasing the half-life of therapeutic proteins in a specific, fast, and reliable way could greatly benefit the discovery of novel protein drugs. In their Communication on page 6880 ff., K. C. Lee, S. Lee, and co-workers conjugate Ni-NTA to poly(ethylene glycol) and then label oligohistidine-tagged therapeutic proteins to improve their stability in vivo without compromising bioactivity.

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