Towards a DNA Nanoprocessor: Reusable Tile-Integrated DNA Circuits
Dr. Yulia V. Gerasimova
Chemistry Department, University of Central Florida, Orlando, FL, 32816 USA
Search for more papers by this authorCorresponding Author
Dr. Dmitry M. Kolpashchikov
Chemistry Department, University of Central Florida, Orlando, FL, 32816 USA
Search for more papers by this authorDr. Yulia V. Gerasimova
Chemistry Department, University of Central Florida, Orlando, FL, 32816 USA
Search for more papers by this authorCorresponding Author
Dr. Dmitry M. Kolpashchikov
Chemistry Department, University of Central Florida, Orlando, FL, 32816 USA
Search for more papers by this authorAbstract
Modern electronic microprocessors use semiconductor logic gates organized on a silicon chip to enable efficient inter-gate communication. Here, arrays of communicating DNA logic gates integrated on a single DNA tile were designed and used to process nucleic acid inputs in a reusable format. Our results lay the foundation for the development of a DNA nanoprocessor, a small and biocompatible device capable of performing complex analyses of DNA and RNA inputs.
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