Strategy Towards Olefin Carbohydroxylation: Transmetalation of 2-Rhodaoxetanes with Organoboron Nucleophiles†
Alexander Dauth
Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6T 1Z1 (Canada), Fax: (+1) 604-822-2847 http://www.chem.ubc.ca/personnel/faculty/love/index.shtml
Search for more papers by this authorCorresponding Author
Prof. Jennifer A. Love
Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6T 1Z1 (Canada), Fax: (+1) 604-822-2847 http://www.chem.ubc.ca/personnel/faculty/love/index.shtml
Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6T 1Z1 (Canada), Fax: (+1) 604-822-2847 http://www.chem.ubc.ca/personnel/faculty/love/index.shtmlSearch for more papers by this authorAlexander Dauth
Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6T 1Z1 (Canada), Fax: (+1) 604-822-2847 http://www.chem.ubc.ca/personnel/faculty/love/index.shtml
Search for more papers by this authorCorresponding Author
Prof. Jennifer A. Love
Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6T 1Z1 (Canada), Fax: (+1) 604-822-2847 http://www.chem.ubc.ca/personnel/faculty/love/index.shtml
Chemistry Department, University of British Columbia, 2036 Main Mall, Vancouver, British Columbia, V6T 1Z1 (Canada), Fax: (+1) 604-822-2847 http://www.chem.ubc.ca/personnel/faculty/love/index.shtmlSearch for more papers by this authorWe thank the following for support of this research: NSERC (Discovery Grant, Research Tools and Instrumentation Grants), University of British Columbia (UGF, Laird and 4YF to A.D.), and Mountain Equipment Coop (A.D.).
Graphical Abstract
Der erste Schritt ist getan: Ein 2-Rhodaoxetan geht eine effiziente Transmetallierung mit zahlreichen funktionalisierten Aryl- und Alkenylboronsäuren ein (siehe Schema). Der Prozess ist mit diversen funktionellen Gruppen verträglich und bildet den ersten Schritt in einer postulierten katalytischen oxidativen Olefinfunktionalisierung.
Supporting Information
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