Expedient Synthesis of Functionalized Conjugated Enynes: Palladium-Catalyzed Bromoalkynylation of Alkynes†
Yibiao Li
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (China), Fax: (+86) 20-8711-2906
Search for more papers by this authorXiaohang Liu
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (China), Fax: (+86) 20-8711-2906
Search for more papers by this authorHuanfeng Jiang Prof. Dr.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (China), Fax: (+86) 20-8711-2906
Search for more papers by this authorZhenning Feng
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (China), Fax: (+86) 20-8711-2906
Search for more papers by this authorYibiao Li
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (China), Fax: (+86) 20-8711-2906
Search for more papers by this authorXiaohang Liu
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (China), Fax: (+86) 20-8711-2906
Search for more papers by this authorHuanfeng Jiang Prof. Dr.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (China), Fax: (+86) 20-8711-2906
Search for more papers by this authorZhenning Feng
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640 (China), Fax: (+86) 20-8711-2906
Search for more papers by this authorWe are grateful to the National Natural Foundation of China (Nos. 20625205, 20772034, and 20932002) and the Doctoral Fund of the Ministry of Education of China (No. 20090172110014) for financial support.
Graphical Abstract
Von der gleichen Seite: Die direkte cis-Addition von Bromalkinen 1 an Alkine 2 in Gegenwart eines Palladium(II)-Katalysators ergibt difunktionalisierte Enine 3 als Produkte. Die Methode bietet einen einfachen Zugang zu Bromalkeninen. Ein ungewöhnlicher Reaktionsmechanismus wird vorgeschlagen.
Supporting Information
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