Enantioselective Synthesis of Axially Chiral Phthalides through Cationic [RhI(H8-binap)]-Catalyzed Cross Alkyne Cyclotrimerization†
Ken Tanaka Prof. Dr.
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, 184-8588, Japan, Fax: (+81) 42-388-7037
Search for more papers by this authorGoushi Nishida
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, 184-8588, Japan, Fax: (+81) 42-388-7037
Search for more papers by this authorAzusa Wada
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, 184-8588, Japan, Fax: (+81) 42-388-7037
Search for more papers by this authorKeiichi Noguchi Prof. Dr.
Instrumentation Analysis Center, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan
Search for more papers by this authorKen Tanaka Prof. Dr.
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, 184-8588, Japan, Fax: (+81) 42-388-7037
Search for more papers by this authorGoushi Nishida
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, 184-8588, Japan, Fax: (+81) 42-388-7037
Search for more papers by this authorAzusa Wada
Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Koganei, Tokyo, 184-8588, Japan, Fax: (+81) 42-388-7037
Search for more papers by this authorKeiichi Noguchi Prof. Dr.
Instrumentation Analysis Center, Tokyo University of Agriculture and Technology, Koganei, Tokyo 184-8588, Japan
Search for more papers by this authorThis work was supported by Mitsubishi Chemical Corporation Fund and Asahi Glass Fund. We thank Takasago International Corporation for the gift of H8-binap.
Graphical Abstract
Einen einfachen Zugang zu axial-chiralen Phthaliden mit ein oder zwei Oxymethylen-Funktionalitäten bietet eine enantioselektive Alkincyclotrimerisierung in Gegenwart des kationischen Komplexes [RhI{(S)-H8-binap}]+. Die axiale Chiralität wird während der Bildung des Benzolrings mit hoher Enantioselektivität eingeführt.
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