Neurological and neuroradiological examination of chronic cannabis smokers

Twelve subjects, eight male and four female, who had smoked on average more than 1 gm of cannabis daily for 10 years, were investigated with a clinical neurological examination and computed tomography (CT) of the brain. No subject had a history of major head trauma or cerebral infection, and just one abused alcohol. Only the subject with a history of alcoholism showed any abnormal cerebral function on clinical tests or any abnormality in the CT scan, compared with normal controls.