Chapter 2
Antitumor Alkaloids in Clinical Use or in Clinical Trials
Muriel Cuendet,
John M. Pezzuto,
Muriel Cuendet
Gerald P. Murphy, Cancer Foundation, 3000 Kent Ave, Suite E 2–400, West Lafayette, IN 47906, USA
Search for more papers by this authorJohn M. Pezzuto
University of Hawaii, Hilo College of Pharmacy, 60 Nowelo St., Suite, Hilo, Hawaii 96720, USA
Search for more papers by this authorMuriel Cuendet,
John M. Pezzuto,
Muriel Cuendet
Gerald P. Murphy, Cancer Foundation, 3000 Kent Ave, Suite E 2–400, West Lafayette, IN 47906, USA
Search for more papers by this authorJohn M. Pezzuto
University of Hawaii, Hilo College of Pharmacy, 60 Nowelo St., Suite, Hilo, Hawaii 96720, USA
Search for more papers by this authorBook Editor(s):Prof. Ernesto Fattorusso,
Prof. Orazio Taglialatela-Scafati,
Prof. Ernesto Fattorusso
Università di Napoli “Federico II”, Dipartimento di Chimica delle Sostanze Naturali, Via D. Montesano, 49, 80131 Napoli, Italy
Search for more papers by this authorProf. Orazio Taglialatela-Scafati
Università di Napoli “Federico II”, Dipartimento di Chimica delle Sostanze Naturali, Via D. Montesano, 49, 80131 Napoli, Italy
Search for more papers by this authorSummary
This chapter contains sections titled:
-
Introduction
-
Antitumor Alkaloids in Clinical Use
-
Vinca Alkaloids
-
Vinblastine (VLB, 1)
-
Vincristine (VCR, 2)
-
Vindesine (VDS, 3)
-
Vinorelbine (VRLB, 4)
-
Vinflunine (VFL, 5)
-
-
Camptothecin and Analogs
-
Camptothecin (CPT, 6)
-
Irinotecan (CPT-11)
-
Topotecan
-
Exatecan
-
Gimatecan
-
Karenitecin
-
Lurtotecan
-
Rubitecan (9-nitrocamptothecin)
-
-
Taxanes
-
Paclitaxel
-
Docetaxel
-
-
-
Antitumor Alkaloids in Clinical Trials
-
Ecteinascidin-743 (Yondelis, Trabectedin)
-
7-Hydroxystaurosporine (UCN-01)
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Ellipticine and Analogs
-
Acronycine and Analogs
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Colchicine and Analogs
-
Ukrain
-
-
Alkaloids Used for MDR Reversal
-
Cinchona Alkaloids
-
Dofequidar Fumarate (MS-209)
-
-
Alkaloids Used for Cancer Prevention
-
Conclusions
-
Acknowledgments
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