The abilities of five polyamino acids (Paa's) to catalyse the asymmetric epoxidation of enones 1–7 under three sets of reaction conditions were compared: polyneo-pentylglycine and polyleucine showed distinct advantages in most circumstances. All five polymers were adsorbed onto silica and from this further study, immobilised polyneo-pentylglycine (PLNSi) and polyleucine (PLLSi) were shown to be the catalysts of choice for the asymmetric epoxidation of less-reactive α,β-unsaturated ketones. Chirality 12:313–317, 2000. © 2000 Wiley-Liss, Inc.

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Volume12, Issue5-6

SPECIAL COMMEMORATIVE ISSUE HONORING PROFESSOR RYOJI NOYORI

2000

Pages 313-317

PaaSiCats: Novel polyamino acid catalysts

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PaaSiCats: Novel polyamino acid catalysts

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