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Cover Picture: ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function / JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia (Isr. J. Chem. 3-4/2013)
- Page: 137
- First Published: 15 April 2013

The cover shows on the left a ConSurf analysis of the influenza neuraminidase protein. The 3D tetramer colored by conservation grades is shown in (A) with maroon indicating the most conserved amino acids, and close-up views (B,C) are shown of one of the conserved regions with the anti-flu drug, oseltamivir (tamiflu) bound; see Celniker et al. for details, page 199. On the right is a page from Proteopedia as viewed on an iPad, via the JSmol viewer, showing a complex of HIV-Protease and Saquinavir (Invirase), the first protease inhibitor approved by the FDA for the treatment of HIV; see Hanson et al. for details, page 207
Contents
Guest Editorial
Guest Editorial: Databases and Bioinformatics Tools
- Page: 143
- First Published: 15 April 2013
Reviews
Single-Base Resolution Sequence-Directed Nucleosome Mapping
- Pages: 144-146
- First Published: 01 March 2013
From Protein Structure to Function via Computational Tools and Approaches
- Pages: 147-156
- First Published: 01 March 2013
Mass Informatics: From Mass Spectrometry Peaks to Biological Pathways
- Pages: 157-165
- First Published: 03 April 2013
Web Tools for Predicting Metal Binding Sites in Proteins
- Pages: 166-172
- First Published: 03 April 2013
Bioinformatics Tools for Marker Discovery in Plant Breeding
- Pages: 173-179
- First Published: 15 April 2013
Protein-Protein Interaction Modeling and Inhibition: The TAU Bioinfo3D Perspective
- Pages: 180-184
- First Published: 15 April 2013
An Overview of Synergistic Data Tools for Biological Scrutiny
- Pages: 185-198
- First Published: 15 April 2013
ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function
- Pages: 199-206
- First Published: 15 April 2013
JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia
- Pages: 207-216
- First Published: 15 April 2013
Full Paper
The Effects of Mutations on Protein Function: A Comparative Study of Three Databases of Mutations in Humans
- Pages: 217-226
- First Published: 15 April 2013