• Issue

    Basic & Clinical Pharmacology & Toxicology: Volume 130, Issue 2

    223-345
    February 2022
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ISSUE INFORMATION

Free Access

Issue Information

  • Pages: 223-224
  • First Published: 12 January 2022

MINI REVIEW

Clinical Pharmacology

Free Access

Home pharmacological therapy in early COVID-19 to prevent hospitalization and reduce mortality: Time for a suitable proposal

Sergio Pandolfi,  Salvatore Chirumbolo,  Giovanni Ricevuti,  Luigi Valdenassi,  Geir Bjørklund,  Roman Lysiuk,  Monica Daniela Doşa,  Larysa Lenchyk,  Serafino Fazio, 
  • Pages: 225-239
  • First Published: 22 November 2021

ORIGINAL ARTICLES

Basic Pharmacology

Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide-induced premature ovarian failure

Shaoyan Zheng,  Mingying Ma,  Yanxia Chen,  Miaoxia Li, 
  • Pages: 240-253
  • First Published: 28 November 2021
Open Access

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha protects a fibrotic liver from partial hepatectomy-induced advanced liver injury through regulating cell cycle arrest

Linzhong Zhang,  Wei Wang,  Lipeng Liu,  Yanghao Zhang,  Xiuying Zhang, 
  • Pages: 254-267
  • First Published: 29 November 2021

Clinical Pharmacology

Pharmacokinetics, safety and bioequivalence of two formulations of progesterone soft capsule in healthy Chinese postmenopausal females: Impacts of a high-fat meal

Huiling Qin,  Liang Zheng,  Yuanyuan Fang,  Yueyue Liu,  Anding Liu,  Jinlian Wu,  Fengjia Zhu,  Jing Chen,  Yijun Fan,  Wei Hu, 
  • Pages: 268-276
  • First Published: 21 November 2021

Gene–gene interactions in the protein kinase C/endothelial nitric oxide synthase axis impact the hypotensive effects of propofol

Gustavo H. Oliveira-Paula,  Daniela A. Pereira,  Lucas C. Pinheiro,  Graziele C. Ferreira,  Waynice N. Paula-Garcia,  Luis V. Garcia,  Riccardo Lacchini,  Marcelo R. Luizon,  Jose E. Tanus-Santos, 
  • Pages: 277-287
  • First Published: 25 November 2021
Open Access

High anticholinergic burden at admission associated with in-hospital mortality in older patients: A comparison of 19 different anticholinergic burden scales

Angela Lisibach,  Giulia Gallucci,  Patrick E. Beeler,  Chantal Csajka,  Monika Lutters, 
  • Pages: 288-300
  • First Published: 26 November 2021

Basic Toxicology

Benchmark dose and the adverse effects of exposure to pendimethalin at low dose in female rats

Marwa F. Gad,  Abdel-Tawab H. Mossa,  Amel A. Refaie,  Noha E. Ibrahim,  Samia M. M. Mohafrash, 
  • Pages: 301-319
  • First Published: 04 November 2021

Clinical Toxicology

Osmolal and anion gaps after acute self-poisoning with agricultural formulations of the organophosphorus insecticides profenofos and diazinon: A pilot study

Jeevan Dhanarisi,  Tanita Maria Tzotzolaki,  Ana-Mariya D. Vasileva,  Matti A. Kjellberg,  Hanna Hakulinen,  Paula Vanninen,  Indika Gawarammana,  Fahim Mohamed,  Knut Erik Hovda,  Michael Eddleston, 
  • Pages: 320-327
  • First Published: 18 November 2021

Acute drug poisonings leading to hospitalization

Charlotte Uggerhøj Andersen,  Lars Peter Nielsen,  Jørn Munkhof Møller,  Anne Estrup Olesen, 
  • Pages: 328-336
  • First Published: 22 November 2021

Potential drug-drug interactions in acute poisonings managed in the intensive care unit: Occurrence, risk factors and relationship to patient severity on admission

Beatrice Mainoli,  Nilza Gonçalves,  Joaquim J. Ferreira,  Bruno Mégarbane, 
  • Pages: 337-345
  • First Published: 07 December 2021