• Issue

    Journal of Thrombosis and Haemostasis: Volume 2, Issue 6

    849-1027
    June 2004
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HISTORICAL SKETCH

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International Normalized Ratios (INR): the first 20 years

L. Poller, 
  • Pages: 849-860
  • First Published: 11 May 2004

DEBATES

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Is the incidence and prevalence of inhibitors greater with recombinant products? Yes

L. M. Aledort, 
  • Pages: 861-862
  • First Published: 08 April 2004
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Is the incidence and prevalence of inhibitors greater with recombinant products? No

J. M. Lusher, 
  • Pages: 863-865
  • First Published: 08 April 2004

COMMENTARIES

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The complex hunt for genes influencing complex disease

L. Almasy, 
  • Pages: 866-867
  • First Published: 11 May 2004
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Has time come for screening for occult cancer in patients with venous thromboembolism?

H. R. Büller, 
  • Pages: 874-875
  • First Published: 11 May 2004
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The ethics of Zelen consent

J. S. Hawkins, 
  • Pages: 882-883
  • First Published: 11 May 2004
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Are the bleeding time and PFA-100® useful in the initial screening of patients with mucocutaneous bleedings of hereditary nature?

M. Cattaneo, 
  • Pages: 890-891
  • First Published: 11 May 2004

IN FOCUS

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Genome scan of venous thrombosis in a pedigree with protein C deficiency

S. J. Hasstedt,  B. T. Scott,  P. W. Callas,  C. Y. Vossen,  F. R. Rosendaal,  G. L. Long,  E. G. Bovill, 
  • Pages: 868-873
  • First Published: 18 March 2004
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Screening for occult cancer in patients with acute deep vein thrombosis or pulmonary embolism

M. Monreal,  A. W. A. Lensing,  M. H. Prins,  M. Bonet,  J. Fernández-Llamazares,  J. Muchart,  P. Prandoni,  J. Angel Jiménez, 
  • Pages: 876-881
  • First Published: 08 April 2004
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Extensive screening for occult malignant disease in idiopathic venous thromboembolism: a prospective randomized clinical trial

A. Piccioli,  A. W. A. Lensing,  M. H. Prins,  A. Falanga,  G. L. Scannapieco,  M. Ieran,  M. Cigolini,  G. B. Ambrosio,  M. Monreal,  A. Girolami,  P. Prandoni,  for the SOMIT Investigators Group , 
  • Pages: 884-889
  • First Published: 08 April 2004
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Template bleeding time and PFA-100® have low sensitivity to screen patients with hereditary mucocutaneous hemorrhages: comparative study in 148 patients

T. Quiroga,  M. Goycoolea,  B. Muñoz,  M. Morales,  E. Aranda,  O. Panes,  J. Pereira,  D. Mezzano, 
  • Pages: 892-898
  • First Published: 11 May 2004

REVIEW ARTICLE

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Recombinant factor VIIa: review of efficacy, dosing regimens and safety in patients with congenital and acquired factor VIII or IX inhibitors

T. Abshire,  G. Kenet, 
  • Pages: 899-909
  • First Published: 11 May 2004

ORIGINAL ARTICLES. Clinical Studies

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Characterization of an immunologic polymorphism (D79H) in the heavy chain of factor V

M. Van Der Neut Kolfschoten,  R. J. Dirven,  S. R. Poort,  R. Van Wijk,  H. L. Vos,  F. R. Rosendaal,  R. M. Bertina, 
  • Pages: 910-917
  • First Published: 24 March 2004
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A common ancestral mutation (C128X) occurring in 11 non-Jewish families from the UK with factor XI deficiency

P. H. B. Bolton-Maggs,  H. Peretz,  R. Butler,  R. Mountford,  S. Keeney,  L. Zacharski,  A. Zivelin,  U. Seligsohn, 
  • Pages: 918-924
  • First Published: 08 April 2004

ORIGINAL ARTICLES. Coagulation

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Activity of a synthetic hexadecasaccharide (SanOrg123781A) in a pig model of arterial thrombosis1

C. Bal dit Sollier,  C. Kang,  N. Berge,  J. P. Herault,  M. Bonneau,  J. M. Herbert,  L. Drouet, 
  • Pages: 925-930
  • First Published: 11 May 2004
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Mutations in the shutter region of antithrombin result in formation of disulfide-linked dimers and severe venous thrombosis

J. Corral,  J. A. Huntington,  R. González-Conejero,  A. Mushunje,  M. Navarro,  P. Marco,  V. Vicente,  R. W. Carrell, 
  • Pages: 931-939
  • First Published: 08 April 2004
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The effects of additional carbohydrate in the coiled-coil region of fibrinogen on polymerization and clot structure and properties: characterization of the homozygous and heterozygous forms of fibrinogen Lima (Aα Arg141→Ser with extra glycosylation)

R. Marchi,  C. L. Arocha-Piñango,  H. Nagy,  M. Matsuda,  J. W. Weisel, 
  • Pages: 940-948
  • First Published: 08 April 2004
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Characterization of a novel human protein C inhibitor (PCI) gene transgenic mouse useful for studying the role of PCI in physiological and pathological conditions

T. Hayashi,  J. Nishioka,  H. Kamada,  K. Asanuma,  H. Kondo,  E. C. Gabazza,  M. Ido,  K. Suzuki, 
  • Pages: 949-961
  • First Published: 08 April 2004

ORIGINAL ARTICLES. Fibrinolysis

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Prion protein stimulates tissue-type plasminogen activator-mediated plasmin generation via a lysine-binding site on kringle 2

Guido Epple,  Wolf-Dieter Schleuning,  Gerhard Kettelgerdes,  Eckart Kőttgen,  Reinhard Geßner,  Michael Praus, 
  • Pages: 962-968
  • First Published: 18 March 2004

ORIGINAL ARTICLES. Platelets

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The P2Y1 receptor plays an essential role in the platelet shape change induced by collagen when TxA2 formation is prevented

P. Mangin,  P. Ohlmann,  A. Eckly,  J.-P. Cazenave,  F. Lanza,  C. Gachet, 
  • Pages: 969-977
  • First Published: 08 April 2004
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Different G protein-coupled signaling pathways are involved in α granule release from human platelets

T. M. Quinton,  S. Murugappan,  S. Kim,  J. Jin,  S. P. Kunapuli, 
  • Pages: 978-984
  • First Published: 08 April 2004
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Delayed thrombocytopenia after treatment with abciximab: a distinct clinical entity associated with the immune response to the drug

B. R. Curtis,  A. Divgi,  M. Garritty,  R. H. Aster, 
  • Pages: 985-992
  • First Published: 13 April 2004
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αIIbβ3 antagonism vs. antiadhesive treatment to prevent platelet interactions with vascular subendothelium

E. Melis,  A. Bonnefoy,  K. Daenens,  H. Yamamoto,  J. Vermylen,  M. F. Hoylaerts, 
  • Pages: 993-1002
  • First Published: 08 April 2004

FORUM

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Laboratory monitoring of low-molecular-weight heparin therapy

J. Hirsh, 
  • Page: 1003
  • First Published: 11 May 2004
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Laboratory monitoring of low-molecular-weight heparin therapy

R. D. Hull, 
  • Pages: 1004-1005
  • First Published: 11 May 2004
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Laboratory monitoring of low-molecular-weight heparin therapy

F. Bachmann, 
  • Pages: 1005-1006
  • First Published: 11 May 2004
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Laboratory monitoring of low-molecular-weight heparin therapy

C. Kearon, 
  • Pages: 1006-1007
  • First Published: 11 May 2004
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Laboratory monitoring of low-molecular-weight heparin therapy

J. N. Fiessinger, 
  • Page: 1007
  • First Published: 11 May 2004

LETTERS TO THE EDITORS

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Venous stasis and thrombin generation

G. Colucci,  H. Stricker,  W. Roggiani,  A. Haeberli,  G. Mombelli, 
  • Pages: 1008-1009
  • First Published: 11 May 2004
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Soluble monocyte cluster domain 163, a new global marker of anti-inflammatory response, is elevated in the first trimester of pregnancy

M. J. Paidas,  D.-H. W. Ku,  B. Davis,  C. J. Lockwood,  Y. S. Arkel, 
  • Pages: 1009-1010
  • First Published: 11 May 2004
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IgG formation to mammalian proteins in hemophilia A patients following treatment with a new recombinant human factor VIII

P. Larson,  C. Zhang,  E. Gorina,  E. Burmeister Getz, 
  • Pages: 1011-1012
  • First Published: 11 May 2004
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Prevalence of protein S deficiency in the Japanese general population: The Suita Study

T. Sakata,  A. Okamoto,  T. Mannami,  H. Tomoike,  T. Miyata, 
  • Pages: 1012-1013
  • First Published: 11 May 2004
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The FcγRIIa His131Arg polymorphism and its association with myocardial infarction

V. Mollaki,  R. P. Steeds,  N. J. Samani,  K. S. Channer,  M. E. Daly, 
  • Pages: 1014-1015
  • First Published: 11 May 2004
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Factor XI gene analysis in thrombophilia and factor XI deficiency

Victor E. A. Gerdes,  Roderik A. Kraaijenhagen,  Esther W. M. Vogels,  Hugo Ten Cate,  Pieter H. Reitsma, 
  • Pages: 1015-1017
  • First Published: 11 May 2004
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Prophylactic and perioperative replacement therapy for acquired factor XIII deficiency

W. Lim,  K. Moffat,  C. P. M. Hayward, 
  • Pages: 1017-1019
  • First Published: 11 May 2004
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Independence of tumor necrosis factor-α-induced adhesion molecule expression from sphingosine 1-phosphate signaling in vascular endothelial cells

Y. Miura,  Y. Yatomi,  T. Ohmori,  M. Osada,  Y. Ozaki, 
  • Pages: 1019-1021
  • First Published: 11 May 2004
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More on: unusual expression of the F9 gene in peripheral lymphocytes hinders investigation of F9 mRNA in hemophilia B patients

Jacqueline A. Cutler,  Michael J. Mitchell,  Geoffrey F. Savidge, 
  • Page: 1021
  • First Published: 11 May 2004
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Choice of replacement therapy for hemophilia—cryoprecipitate issues: a rebuttal

A. Farrugia,  P. Giangrande, 
  • Pages: 1022-1023
  • First Published: 11 May 2004
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WFH policy on selection of coagulation factor concentrates: a rebuttal

P. Giangrande,  B. O'Mahony,  D. Page,  B. Evatt, 
  • Page: 1023
  • First Published: 11 May 2004
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Effect of prolonged sitting on thrombin generation: not evidenced yet: reply to a rebuttal

Hans Stricker,  Giuseppe Colucci,  Giorgio Mombelli, 
  • Pages: 1024-1025
  • First Published: 11 May 2004

ANNOUNCEMENTS

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ANNOUNCEMENTS

  • Page: 1026
  • First Published: 06 April 2004

ERRATUM

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ERRATUM

  • Page: 1027
  • First Published: 16 September 2008

FORTHCOMING

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Forthcoming Articles in the July Issue

  • First Published: 28 June 2008