• Issue

    Arthritis & Rheumatism: Volume 65, Issue 2

    291-542
    February 2013
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In This Issue

In this issue

  • First Published: 28 January 2013

Special Articles

Review: Central pain mechanisms in the rheumatic diseases: Future directions

Kristine Phillips,  Daniel J. Clauw, 
  • Pages: 291-302
  • First Published: 08 October 2012

Editorial: The efficacy of rituximab in refractory myositis: The jury is still out

Marianne de Visser, 
  • Pages: 303-306
  • First Published: 02 November 2012

Editorial: Methotrexate saves lives: A pearl of observational research

Robert B. M. Landewé, 
  • Pages: 307-309
  • First Published: 08 October 2012

Editorial: Valgus alignment and lateral compartment knee osteoarthritis: A biomechanical paradox or new insight into knee osteoarthritis?

Thomas P. Andriacchi, 
  • Pages: 310-313
  • First Published: 30 November 2012

Myositis

Rituximab in the treatment of refractory adult and juvenile dermatomyositis and adult polymyositis: A randomized, placebo-phase trial†

Chester V. Oddis,  Ann M. Reed,  Rohit Aggarwal,  Lisa G. Rider,  Dana P. Ascherman,  Marc C. Levesque,  Richard J. Barohn,  Brian M. Feldman,  Michael O. Harris-Love,  Diane C. Koontz,  Noreen Fertig,  Stephanie S. Kelley,  Sherrie L. Pryber,  Frederick W. Miller,  Howard E. Rockette,  and the RIM Study Group , 
  • Pages: 314-324
  • First Published: 02 November 2012

Rheumatoid Arthritis

Association of brain functional magnetic resonance activity with response to tumor necrosis factor inhibition in rheumatoid arthritis

Juergen Rech,  Andreas Hess,  Stephanie Finzel,  Silke Kreitz,  Marina Sergeeva,  Matthias Englbrecht,  Arnd Doerfler,  Marc Saake,  Georg Schett, 
  • Pages: 325-333
  • First Published: 13 December 2012

Propensity-adjusted association of methotrexate with overall survival in rheumatoid arthritis

Mary Chester M. Wasko,  Abhijit Dasgupta,  Helen Hubert,  James F. Fries,  Michael M. Ward, 
  • Pages: 334-342
  • First Published: 08 October 2012

Clinical Images

Charcot's arthropathy of the spine

Giulio Cavalli MD,  Teresa D'Aliberti MD, 
  • Page: 342
  • First Published: 01 November 2012

Experimental Arthritis

p27Kip1 inhibits systemic autoimmunity through the control of Treg cell activity and differentiation

Marcos Iglesias,  Jorge Postigo,  Inés Santiuste,  Jovanna González,  Luis Buelta,  Esther Tamayo,  Jesús Merino,  Ramón Merino, 
  • Pages: 343-354
  • First Published: 02 November 2012

Osteoarthritis

Valgus malalignment is a risk factor for lateral knee osteoarthritis incidence and progression: Findings from the multicenter osteoarthritis study and the osteoarthritis initiative

David T. Felson,  Jingbo Niu,  K. Douglas Gross,  Martin Englund,  Leena Sharma,  T. Derek V. Cooke,  Ali Guermazi,  Frank W. Roemer,  Neil Segal,  Joyce M. Goggins,  C. Elizabeth Lewis,  Charles Eaton,  Michael C. Nevitt, 
  • Pages: 355-362
  • First Published: 30 November 2012

Discordance between pain and radiographic severity in knee osteoarthritis: Findings from quantitative sensory testing of central sensitization

Patrick H. Finan,  Luis F. Buenaver,  Sara C. Bounds,  Shahid Hussain,  Raymond J. Park,  Uzma J. Haque,  Claudia M. Campbell,  Jennifer A. Haythornthwaite,  Robert R. Edwards,  Michael T. Smith, 
  • Pages: 363-372
  • First Published: 07 September 2012

Brief Report: Differences in multijoint symptomatic osteoarthritis phenotypes by race and sex: The Johnston County Osteoarthritis Project†

Amanda E. Nelson,  Yvonne M. Golightly,  Jordan B. Renner,  Todd A. Schwartz,  Virginia B. Kraus,  Charles G. Helmick,  Joanne M. Jordan, 
  • Pages: 373-377
  • First Published: 28 January 2013

Mitochondrial dysfunction in osteoarthritis is associated with down-regulation of superoxide dismutase 2†

Christos Gavriilidis,  Satomi Miwa,  Thomas von Zglinicki,  Robert W. Taylor,  David A. Young, 
  • Pages: 378-387
  • First Published: 08 November 2012

Quantitative imaging of murine osteoarthritic cartilage by phase-contrast micro–computed tomography

Merry Z. C. Ruan,  Brian Dawson,  Ming-Ming Jiang,  Francis Gannon,  Michael Heggeness,  Brendan H. L. Lee, 
  • Pages: 388-396
  • First Published: 01 November 2012

Src and fibroblast growth factor 2 independently regulate signaling and gene expression induced by experimental injury to intact articular cartilage

Fiona E. Watt,  Heba M. Ismail,  Athanasios Didangelos,  Matthew Peirce,  Tonia L. Vincent,  Robin Wait,  Jeremy Saklatvala, 
  • Pages: 397-407
  • First Published: 01 November 2012

Chondrocyte Biology

Stimulation of superficial zone protein accumulation by hedgehog and Wnt signaling in surface zone bovine articular chondrocytes

Takashi Iwakura,  Atsuyuki Inui,  A. Hari Reddi, 
  • Pages: 408-417
  • First Published: 01 November 2012

Zone-specific gene expression patterns in articular cartilage

Shawn P. Grogan,  Stuart F. Duffy,  Chantal Pauli,  James A. Koziol,  Andrew I. Su,  Darryl D. D'Lima,  Martin K. Lotz, 
  • Pages: 418-428
  • First Published: 01 November 2012

β-catenin regulates parathyroid hormone/parathyroid hormone–related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C-terminal region of the receptor

Fumiko Yano,  Taku Saito,  Naoshi Ogata,  Toshiko Yamazawa,  Masamitsu Iino,  Ung-il Chung,  Hiroshi Kawaguchi, 
  • Pages: 429-435
  • First Published: 02 November 2012

Clinical Images

Communicating synovial pseudocyst in small joint of the hand assessed by ultrasound

Angel Checa MD,  Kiplee Bell MS, PA-C,  Carolyn R. O'Connor MD, 
  • Page: 435
  • First Published: 01 November 2012

Bone Biology

Interleukin-17A stimulates granulocyte–macrophage colony-stimulating factor release by murine osteoblasts in the presence of 1,25-dihydroxyvitamin D3 and inhibits murine osteoclast development in vitro

Deepak Balani,  Daniel Aeberli,  Willy Hofstetter,  Michael Seitz, 
  • Pages: 436-446
  • First Published: 01 November 2012

Systemic Lupus Erythematosus

Down-regulation of interferon signature in systemic lupus erythematosus patients by active immunization with interferon α–kinoid†

Bernard R. Lauwerys,  Eric Hachulla,  François Spertini,  Estibaliz Lazaro,  Christian Jorgensen,  Xavier Mariette,  Edwige Haelterman,  Géraldine Grouard-Vogel,  Bernard Fanget,  Olivier Dhellin,  Pierre Vandepapelière,  Frédéric A. Houssiau, 
  • Pages: 447-456
  • First Published: 30 November 2012

IgG anti–NR2 glutamate receptor autoantibodies from patients with systemic lupus erythematosus activate endothelial cells

Taku Yoshio,  Hiroshi Okamoto,  Shunsei Hirohata,  Seiji Minota, 
  • Pages: 457-463
  • First Published: 10 October 2012

Antiphospholipid Syndrome

A pilot open-label phase II trial of rituximab for non-criteria manifestations of antiphospholipid syndrome†

Doruk Erkan,  JoAnn Vega,  Glendalee Ramón,  Elizabeth Kozora,  Michael D. Lockshin, 
  • Pages: 464-471
  • First Published: 02 November 2012

Systemic Sclerosis

PLD4 as a novel susceptibility gene for systemic sclerosis in a Japanese population

Chikashi Terao,  Koichiro Ohmura,  Yasushi Kawaguchi,  Tetsuya Nishimoto,  Aya Kawasaki,  Kazuhiko Takehara,  Hiroshi Furukawa,  Yuta Kochi,  Yuko Ota,  Katsunori Ikari,  Shinichi Sato,  Shigeto Tohma,  Ryo Yamada,  Kazuhiko Yamamoto,  Michiaki Kubo,  Hisashi Yamanaka,  Masataka Kuwana,  Naoyuki Tsuchiya,  Fumihiko Matsuda,  Tsuneyo Mimori, 
  • Pages: 472-480
  • First Published: 01 November 2012

Tumor necrosis factor–costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts

Thomas Hügle,  Steven O'Reilly,  Rachel Simpson,  Marina D. Kraaij,  Venetia Bigley,  Matthew Collin,  Anja Krippner-Heidenreich,  Jacob M. van Laar, 
  • Pages: 481-491
  • First Published: 08 October 2012

Alpha2-antiplasmin regulates the development of dermal fibrosis in mice by prostaglandin F2α synthesis through adipose triglyceride lipase/calcium-independent phospholipase A2

Yosuke Kanno,  Eri Kawashita,  Akiko Kokado,  Kiyotaka Okada,  Shigeru Ueshima,  Osamu Matsuo,  Hiroyuki Matsuno, 
  • Pages: 492-502
  • First Published: 01 November 2012

Vasculitis

Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation

Chie Miyabe,  Yoshishige Miyabe,  Noriko N. Miura,  Kei Takahashi,  Yuya Terashima,  Etsuko Toda,  Fumiko Honda,  Tomohiro Morio,  Naoko Yamagata,  Naohito Ohno,  Koichi Shudo,  Jun-Ichi Suzuki,  Mitsuaki Isobe,  Kouji Matsushima,  Ryoji Tsuboi,  Nobuyuki Miyasaka,  Toshihiro Nanki, 
  • Pages: 503-512
  • First Published: 30 November 2012

Pediatric Rheumatology

Clinical and transcriptional response to the long-acting interleukin-1 blocker canakinumab in Blau syndrome–related uveitis

Gabriele Simonini,  Zhaohui Xu,  Roberto Caputo,  Cinzia De Libero,  Ilaria Pagnini,  Virginia Pascual,  Rolando Cimaz, 
  • Pages: 513-518
  • First Published: 01 November 2012

Fibromyalgia

Association of fibromyalgia with altered skeletal muscle characteristics which may contribute to postexertional fatigue in postmenopausal women†

Ratchakrit Srikuea,  T. Brock Symons,  Douglas E. Long,  Jonah D. Lee,  Yu Shang,  Peter J. Chomentowski,  Guoqiang Yu,  Leslie J. Crofford,  Charlotte A. Peterson, 
  • Pages: 519-528
  • First Published: 01 November 2012

Low-dose naltrexone for the treatment of fibromyalgia: Findings of a small, randomized, double-blind, placebo-controlled, counterbalanced, crossover trial assessing daily pain levels†

Jarred Younger,  Noorulain Noor,  Rebecca McCue,  Sean Mackey, 
  • Pages: 529-538
  • First Published: 28 January 2013

Clinical Images

Milwaukee shoulder syndrome affecting the elbow

Paul Ornetti MD, PhD,  Nathalie Vernier MD,  Clémentine Fortunet MD, 
  • Page: 538
  • First Published: 01 November 2012

Letters

The effect of triple therapy versus etanercept plus methotrexate in rheumatoid arthritis: Comment on the article by Moreland et al

Niels Graudal MD, DMSc,  Gesche Jürgens MD, PhD, 
  • Page: 539
  • First Published: 02 November 2012

Reply

Larry W. Moreland MD, 
  • Pages: 539-540
  • First Published: 02 November 2012

Expression of free HLA class I heavy chains in an immune-privileged site: Comment on the article by Taurog et al

Andreas Ziegler PhD,  Barbara Uchanska-Ziegler PhD,  Astrid Blaschitz MD,  Heinz Hutter PhD,  Gottfried Dohr MD, 
  • Pages: 540-541
  • First Published: 02 November 2012

Reply

Joel D. Taurog MD, 
  • Page: 541
  • First Published: 02 November 2012

Pathogenic relevance of anti–citrullinated vimentin antibodies: Comment on the article by Montes et al

Diane van der Woude MD, PhD,  Hans-Ulrich Scherer MD,  Tom W. J. Huizinga MD, PhD,  René E. M. Toes PhD, 
  • Pages: 541-542
  • First Published: 10 October 2012

Reply

Ariana Montes MSc,  Eva Perez-Pampin MD,  Manuel Calaza PhD,  Juan J. Gomez-Reino MD, PhD,  Antonio Gonzalez MD, PhD, 
  • Page: 542
  • First Published: 10 October 2012

ACR Announcements

ACR announcements

  • First Published: 28 January 2013