Arthritis & Rheumatism: Vol 62, No 3

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In This Issue

In this issue

Editorials

Should antibodies to high-density lipoprotein cholesterol and its components be measured in all systemic lupus erythematosus patients to predict risk of atherosclerosis?

The synovial lining micromass system: Toward rheumatoid arthritis in a dish?

Review

The role of synovial macrophages and macrophage-produced mediators in driving inflammatory and destructive responses in osteoarthritis

Autoimmunity

Autoimmune diseases in women with Turner's Syndrome

Cardiovascular Disease

Cardiovascular disease in patients with inflammatory rheumatic disease is associated with up-regulation of markers of inflammation in cardiac microvessels and cardiomyocytes

Search for Next Editor, Arthritis Care & Research

Search for next Editor, Arthritis Care & Research (2011–2016 Term)

Rheumatoid Arthritis Clinical Studies

Two-year clinical and radiographic results with combination etanercept–methotrexate therapy versus monotherapy in early rheumatoid arthritis: A two-year, double-blind, randomized study†

Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll-like receptors

Gene expression profiling in autoantibody-positive patients with arthralgia predicts development of arthritis†

Clinical Images

Clinical images: Calcifying pseudoneoplasm of the neuraxis

Rheumatoid Arthritis Basic Science Studies

Evidence of epistasis between TNFRSF14 and TNFRSF6B polymorphisms in patients with rheumatoid arthritis

Angiogenesis and blood vessel stability in inflammatory arthritis

Blocking ERK-1/2 reduces tumor necrosis factor α–induced interleukin-18 bioactivity in rheumatoid arthritis synovial fibroblasts by induction of interleukin-18 binding protein A

Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction

Synovium

Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture

Experimental Arthritis

Neutrophils in a mouse model of autoantibody-mediated arthritis: Critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function−associated antigen 1

Adeno-associated virus type 5–mediated intraarticular administration of tumor necrosis factor small interfering RNA improves collagen-induced arthritis

Osteoarthritis

Comparative analysis of gene expression profiles between primary knee osteoarthritis and an osteoarthritis endemic to Northwestern China, Kashin-Beck disease

Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family

Cartilage Biology

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

Proteomic analysis by two-dimensional electrophoresis to identify the normal human chondrocyte proteome stimulated by tumor necrosis factor α and interleukin-1β

Trefoil factor 3 is induced during degenerative and inflammatory joint disease, activates matrix metalloproteinases, and enhances apoptosis of articular cartilage chondrocytes

Akt1 in murine chondrocytes controls cartilage calcification during endochondral ossification under physiologic and pathologic conditions

Clinical Image

Clinical Image: Perihepatitis in systemic lupus erythematosus

Systemic Lupus Erythematosus

Erythrocyte C3d and C4d for monitoring disease activity in systemic lupus erythematosus

Antibodies to apolipoprotein A-I, high-density lipoprotein, and C-reactive protein are associated with disease activity in patients with systemic lupus erythematosus

Antimalarial treatment may have a time-dependent effect on lupus survival: Data from a multinational Latin American inception cohort

The protective effect of antimalarial drugs on thrombovascular events in systemic lupus erythematosus

Antiphospholipid Syndrome

Differential expression of protease-activated receptors in monocytes from patients with primary antiphospholipid syndrome

Systemic Sclerosis

Endothelin 1 contributes to the effect of transforming growth factor β1 on wound repair and skin fibrosis

Association of the FAM167A–BLK region with systemic sclerosis

Clinical Images

Clinical Images: Gout revealed on arthroscopy after minor injury

Childhood Arthritis

Biologic predictors of extension of oligoarticular juvenile idiopathic arthritis as determined from synovial fluid cellular composition and gene expression

Letter

Rituximab monotherapy, rather than rituximab plus antiviral drugs, for initial treatment of severe hepatitis C virus–associated mixed cryoglobulinemia syndrome: Comment on the article by Terrier et al

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Letter

Bone structural changes and hip osteoarthritis: Comment on the article by Javaid et al

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Related Titles

Two-year clinical and radiographic results with combination etanercept–methotrexate therapy versus monotherapy in early rheumatoid arthritis: A two-year, double-blind, randomized study ^†

Gene expression profiling in autoantibody-positive patients with arthralgia predicts development of arthritis ^†