Arthritis & Rheumatism: Vol 60, No 1

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Arthritis & Rheumatism: Volume 60, Issue 1

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In This Issue

In this issue

Editorial

The future of folic acid antagonist therapy in rheumatoid arthritis

Naturally acquired microchimerism: For better or for worse

Tumor necrosis factor receptor–associated periodic syndrome: Toward a molecular understanding of the systemic autoinflammatory diseases

Rheumatoid Arthritis Clinical Studies

Folate receptor β as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients

Independent association of rheumatoid arthritis with increased left ventricular mass but not with reduced ejection fraction

Different patterns of associations with anti–citrullinated protein antibody–positive and anti–citrullinated protein antibody–negative rheumatoid arthritis in the extended major histocompatibility complex region

Association of the TRAF1/C5 locus with increased mortality, particularly from malignancy or sepsis, in patients with rheumatoid arthritis

The chromosome 7q region association with rheumatoid arthritis in females in a british population is not replicated in a North American case–control series

Rheumatoid Arthritis Basic Science Studies

Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci

Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein α

Transfer of the shared epitope through microchimerism in women with rheumatoid arthritis

Sjögrens Syndrome

Systems biology analysis of sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands

Experimental Arthritis

Inflammatory lesions of the spine on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis: Evidence of a relationship between inflammation and new bone formation

Clinical Images

Clinical images: Ocular mycobacterium infection in ankylosing spondylitis

Experimental Arthritis

Tolerization with Hsp65 induces protection against adjuvant-induced arthritis by modulating the antigen-directed interferon-γ, interleukin-17, and antibody responses

Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice

Search for Next Editor

Search for next editor, Arthritis & Rheumatism (2010–2015 term)

Cell Biology

CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice

Cartilage Biology

Modulation of lubricin biosynthesis and tissue surface properties following cartilage mechanical injury

Effect of interleukin-1β on osteogenic protein 1–induced signaling in adult human articular chondrocytes

Blocking vascular endothelial growth factor with soluble Flt-1 improves the chondrogenic potential of mouse skeletal muscle–derived stem cells

Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type x collagen gene

Errata

Errata

Osteoarthritis

Differential expression of αB-crystallin and evidence of its role as a mediator of matrix gene expression in osteoarthritis

Quadriceps strength and the risk of cartilage loss and symptom progression in knee osteoarthritis

Clinical Images

Clinical Images: Lumbar spondylolisthesis caused by tophaceous gout

Systemic Lupus Erythematosus

CXCR3+CD4+ T cells are enriched in inflamed kidneys and urine and provide a new biomarker for acute nephritis flares in systemic lupus erythematosus patients

Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus

Systemic Sclerosis

Treatment with imatinib prevents fibrosis in different preclinical models of systemic sclerosis and induces regression of established fibrosis

Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: A new perspective for pulmonary fibrosis

Requirement of transforming growth factor β–activated kinase 1 for transforming growth factor β–induced α-smooth muscle actin expression and extracellular matrix contraction in fibroblasts

Childhood Arthritis

Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis

Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis

Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis

Autoinflammatory Disease

Successful treatment of idiopathic recurrent pericarditis in children with interleukin-1β receptor antagonist (anakinra): An unrecognized autoinflammatory disease?

Novel markers of inflammation identified in tumor necrosis factor receptor–associated periodic syndrome (TRAPS) by transcriptomic analysis of effects of TRAPS-associated tumor necrosis factor receptor type I mutations in an endothelial cell line

Gout

Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal–induced murine peritoneal model of acute gout

Hemophilic Arthropathy

The combination of the biomarkers urinary C-terminal telopeptide of type II collagen, serum cartilage oligomeric matrix protein, and serum chondroitin sulfate 846 reflects cartilage damage in hemophilic arthropathy

Clinical Image

Clinical image: Brain perfusion single-photon–emission computed tomography findings in a patient with an asymmetric fibromyalgia syndrome

Fibromyalgia

Sodium oxybate relieves pain and improves function in fibromyalgia syndrome: A randomized, double-blind, placebo-controlled, multicenter clinical trial†

Letters

Reply to letter by Volkman commenting on the possible onset of seronegative disease in Lyme arthritis

Thymic function and immune senescence in juvenile idiopathic arthritis: Comment on the article by Prelog et al

Reply

Reply

Clinical Images

Clinical images: Hypertension due to otherwise asymptomatic, complete aortic occlusion in Takayasu arteritis

ACR Announcement

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Sodium oxybate relieves pain and improves function in fibromyalgia syndrome: A randomized, double-blind, placebo-controlled, multicenter clinical trial ^†