• Issue

    Journal of Pharmaceutical Sciences: Volume 69, Issue 6

    fmi, I-IV, 621-754
    June 1980
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  • Page: fmi
  • First Published: June 1980

Editorial

Where have all the researchers gone?

  • Page: I
  • First Published: June 1980

Open Forum

Suspension theory—psychological/physiological states

Bernard Ecanow, 
  • Page: IV
  • First Published: June 1980

Research Articles

Cost evaluation of alternative pharmaceutical tableting processes by simulation

R. M. Franz,  G. S. Banker,  J. R. Buck,  G. E. Peck, 
  • Pages: 621-628
  • First Published: June 1980

Derivative and graphical procedures for correction of irrelevant UV spectrophotometric absorption in changeable matrixes

J. Traveset,  V. Such,  R. Gonzalo,  E. Gelpi, 
  • Pages: 629-633
  • First Published: June 1980

Comparative pharmacokinetics of coumarin anticoagulants XLVI: Effect of treatment with phenobarbital on pharmacokinetics of (S)-(−)-warfarin in rats

Avraham Yacobi,  John T. Slattery,  Gerhard Levy, 
  • Pages: 634-636
  • First Published: June 1980

Stability of brompton mixtures: Determination of heroin (diacetylmorphine) and cocaine in presence of their hydrolysis products

G. K. Poochikian,  J. C. Cradock, 
  • Pages: 637-639
  • First Published: June 1980

GLC–mass spectrometric procedure with selected-ion monitoring for determination of plasma concentrations of unlabeled and labeled barbital following simultaneous oral and intravenous administration

F. Varin,  C. Marchand,  P. Larochelle,  K. K. Midha, 
  • Pages: 640-643
  • First Published: June 1980

Permeability of everted rat small intestine to lidocaine and derivatives

Peter J. Cascella,  Stuart Feldman, 
  • Pages: 643-647
  • First Published: June 1980

Lipophilicity, molecular weight, and drug action: Reexamination of parabolic and bilinear models

Eric J. Lien,  P. H. Wang, 
  • Pages: 648-650
  • First Published: June 1980

Particle-size analysis of pharmaceutical powders

L. J. Beaubien,  A. J. Vanderwielen, 
  • Pages: 651-655
  • First Published: June 1980

Simultaneous partitioning and hydrolysis kinetics of amoxicillin and ampicillin

Eric Tomlinson,  Robert E. Notari,  Peter R. Byron, 
  • Pages: 655-658
  • First Published: June 1980

Extended hildebrand approach: Solubility of caffeine in dioxane–water mixtures

A. Adjei,  J. Newburger,  A. Martin, 
  • Pages: 659-661
  • First Published: June 1980

Effects of different buffer species on partition coefficients of drugs used in quantitative structure–activity relationships

Pou-Hsiung Wang,  Eric J. Lien, 
  • Pages: 662-668
  • First Published: June 1980

Effect of polybasic acids on structure of aluminum hydroxycarbonate gel

Ming K. Wang,  Joe L. White,  Stanley L. Hem, 
  • Pages: 668-671
  • First Published: June 1980

Deiodination kinetics of water-soluble radiopaques

Yu-Chang John Wang, 
  • Pages: 671-675
  • First Published: June 1980

Solubility of polar organic solutes in nonaqueous systems: Role of specific interactions

Bradley D. Anderson,  J. Howard Rytting,  Takeru Higuchi, 
  • Pages: 676-680
  • First Published: June 1980

GLC determination of bretylium in biological fluids

Chii-Ming Lai,  Burde L. Kamath,  James E. Carter,  Paul Erhardt,  Zee M. Look,  Avraham Yacobi, 
  • Pages: 681-683
  • First Published: June 1980

GLC–mass spectrometric determination of maprotiline and its major metabolite using stable isotope-labeled analog as internal standard

Satya P. Jindal,  Theresa Lutz,  Per Vestergaard, 
  • Pages: 684-687
  • First Published: June 1980

Identification and analysis of persistent contaminants associated with gemcadiol

J. Philip,  D. H. Szulczewski, 
  • Pages: 687-691
  • First Published: June 1980

Preliminary model for streptozocin metabolism in mice

Jonas M. Weissbrod,  Rakesh K. Jain, 
  • Pages: 691-694
  • First Published: June 1980

Antihyperlipidemic activity of sesquiterpene lactones and related compounds

I. H. Hall,  K. H. Lee,  C. O. Starnes,  O. Muraoka,  Y. Sumida,  T. G. Waddell, 
  • Pages: 694-697
  • First Published: June 1980

Evaluation of nystatin stability using tristimulus colorimetry

John E. Fairbrother,  William F. Heyes,  Geoffrey Clarke,  Peter R. Wood, 
  • Pages: 697-700
  • First Published: June 1980

High-pressure liquid chromatographic determination of sulfamethazine residues in beef tissues

David Seymour,  B. Dean Rupe, 
  • Pages: 701-703
  • First Published: June 1980

Teratogenic potential of cocaine hydrochloride in CF-1 mice

Michael P. Mahalik,  Ronald F. Gautieri,  David E. Mann Jr., 
  • Pages: 703-706
  • First Published: June 1980

Sensitive GLC–mass spectrometric determination of chlorpheniramine in serum

John A. Thompson,  Fred H. Leffert, 
  • Pages: 707-710
  • First Published: June 1980

Determination of chlorambucil in plasma by GLC with selected-ion monitoring

Hans Ehrsson,  Staffan Eksborg,  Inger Wallin,  Yvonne Måde,  Bo Joansson, 
  • Pages: 710-712
  • First Published: June 1980

Video characterization of flume patterns of inhalation aerosols

S. Miszuk,  B. M. Gupta,  F. C. Chen,  C. Clawans,  J. Z. Knapp, 
  • Pages: 713-717
  • First Published: June 1980

Microcolumn chromatographic cleanup and GLC determination of 11-methyl-16,16-dimethylprostaglandin E2 in polyethylene glycol 400 solutions

Ronald F. Quadrel,  Soohee Lee,  Frances M. Bogdansky, 
  • Pages: 718-720
  • First Published: June 1980

Production and characterization of specific antibody for radioimmunoassay of procainamide

P. Mojaverian,  G. D. Chase, 
  • Pages: 721-724
  • First Published: June 1980

Hydrolysis of tetrakis-μ-acetylsalicylato-dicopper(II)

A. A. Alich,  L. E. Wittmers, 
  • Pages: 725-727
  • First Published: June 1980

Notes

Quantitation of the antineoplastic agent indicine-N-oxide in human plasma by differential pulse polarography

Madeline McComish,  Itamar Bodek,  Alan R. Branfman, 
  • Pages: 727-729
  • First Published: June 1980

Synthesis of phenylurethans of 1,2-dialkyl-4-pyrazolidinols as anticonvulsant agents

Milton J. Kornet, 
  • Pages: 729-731
  • First Published: June 1980

Evaluation of 99mTc-labeled iminodiacetic acid derivatives of substituted 2-aminopyrroles as hepatobiliary imaging agents I

Carl M. Dejuliis,  Bernard W. Graham,  Ronald J. Mattson,  J. Walter Sowell Sr., 
  • Pages: 731-732
  • First Published: June 1980

Antiproliferative effects of inhibitors of polyamine synthesis in tumors of neural origin

Sharon K. Chapman,  Susan K. Glant, 
  • Pages: 733-735
  • First Published: June 1980

Antineoplastic evaluation of pacific basin marine algae

M. Kashiwagi,  J. S. Mynderse,  R. E. Moore,  T. R. Norton, 
  • Pages: 735-738
  • First Published: June 1980

Communications

Ocular absorption of propranolol in rabbits

A. Hussain,  S. Hirai,  J. Sieg, 
  • Pages: 738-739
  • First Published: June 1980

Comparative in vitro and in vivo antifungal activity of tolnaftate and various undecylenates

David Loebenberg,  Raulo Parmegiani,  Margaret Hanks,  J. Allan Waitz, 
  • Pages: 739-741
  • First Published: June 1980

Comparative in vitro and in vivo antifungal activity of tolnaftate and various undecylenates: A rebuttal

Lewis P. Amsel, 
  • Pages: 741-742
  • First Published: June 1980

Hygroscopicity of poorly soluble porous substances

J. T. Carstensen,  P. Touré,  L. Van Campen,  G. Zografi, 
  • Pages: 742-744
  • First Published: June 1980

Enhancement of rectal absorption of drugs by adjuvants

Toshiaki Nishihata,  J. Howard Rytting,  Takeru Higuchi, 
  • Pages: 744-745
  • First Published: June 1980

Kinetic characterization of liposomes

Toshihisa Yotsuyanagi,  Ken Ikeda, 
  • Pages: 745-746
  • First Published: June 1980

Quantitative change in metabolic fate of drug related to serum protein binding

Gerhard Levy, 
  • Pages: 746-747
  • First Published: June 1980

Polyethylene glycols as solvents in implantable osmotic pumps

Peter C. Will,  Ronald N. Cortright,  Ulrich Hopfer, 
  • Pages: 747-749
  • First Published: June 1980

Disintegration test for hard gelatin capsules

Jerry Polesuk, 
  • Page: 749
  • First Published: June 1980

Effect of smoking on binding of lidocaine to human serum proteins

P. J. McNamara,  R. L. Slaughter,  J. P. Visco,  C. M. Elwood,  J. H. Siegel,  D. Lalka, 
  • Pages: 749-751
  • First Published: June 1980

Effect of changes in plasma protein binding on half-life of drugs

Francis L. S. Tse, 
  • Pages: 751-752
  • First Published: June 1980

Book Reviews

Foundations of molecular pharmacology, Vol. 1: Medicinal and pharmaceutical chemistry. By J. B. Stenlake. The Athlone Press, University of London, Four Gower St., London WC1, England. 1979. 936 pp. 15 × 23 cm. Price $90.00

Eugene I. Isaacson, 
  • Page: 752
  • First Published: June 1980

Chlorophyll organization and energy transfer in photosynthesis. (Ciba Foundation Symposium 61.) Elsevier/North-Holland Inc., 52 Vanderbilt Ave., New York, NY 10017. 1979. 374 pp. 16 × 24 cm

P. G. Vincent, 
  • Page: 753
  • First Published: June 1980

Drug toxicity. Edited by J. W. Gorrod. Taylor and Francis Ltd., 10–14 Macklin St., London WC2B 5WF, England. 1979. 326 pp. 15 × 23 cm

Anthony T. Dren, 
  • Page: 753
  • First Published: June 1980

Comprehensive organic chemistry. (A series of six volumes.) Edited by Sir D. Barton and W. D. Ollis. Pergamon, Oxford, England. 1979. 18.5 × 27.5 cm. Price $1250. Vol. 1: edited by J. F. Stoddart, xiii + 1227 pp. Vol. 2: edited by I. O. Sutherland, xiii + 1329 pp. Vol. 3: edited by D. N. Jones, xv + 1323 pp. Vol. 4: edited by P. G. Sammes, xiii + 1228 pp. Vol. 5: edited by E. Haslam, xv + 1205 pp. Vol 6: edited by C. J. Drayton, xv + 1628 pp

William O. Foye, 
  • Pages: 753-754
  • First Published: June 1980

Computer assisted studies of chemical structure and biological function. By A. J. Stuper, W. E. Brügger, and P. C. Jurs. Wiley, One Wiley Drive, Somerset, NJ 08873. 1979. xi + 220 pp. 16 × 23 cm. Price $23.50

Arthur Cammarata, 
  • Page: 754
  • First Published: June 1980

Antibiotics: Isolation, separation, and purification. Edited by Marvin J. Weinstein and Gerald H. Wagman. (Journal of Chromatography Library, Vol. 15.) Elsevier/North-Holland Inc., 52 Vanderbilt Ave., New York, NY 10017. 1978. 769 pp. 16 × 24 cm. Price $84.75

George B. Selzer, 
  • Page: 754
  • First Published: June 1980