Study workflow. Left, 49 chronic heart failure (HF) patients and 49 healthy controls (HCs) undergoing brain structural MRI and cognitive assessment were retrospectively included. Right, Abnormal cortical thickness and sulcal depth were positively correlated with cognitive performance.

Cerebellar rTMS improved sway index under eyes closed-foam surface condition in young healthy adults, whereas M1 rTMS did not show any improvement. Findings suggest a unique role of cerebellum in reactive balance performance during the most sensory deprived conditions.

There was a significant main effect of sex in five cortical regions, where gyrification was increased in women compared to men (women > men). These regions were located on the lateral surface of the brain, specifically left rostral middle frontal (Cluster 1), left caudal middle frontal (Cluster 2), left inferior parietal (Cluster 3), right inferior frontal (Cluster 4) and right occipital (Cluster 5). There was no cortical region where gyrification was increased in men compared to women.

MDS and RTT are neurodevelopmental disorders; MDS arises from MECP2 and IRAK1 gene duplication, while RTT results from MECP2 mutations. Using multi-omics analysis on fibroblasts from MDS, carrier mothers, and patients with RTT, we identified distinct dysregulated biological processes and potential biomarker genes, revealing unexpected molecular differences among the cohorts.

Intermittent theta burst stimulation (iTBS) over dorsal premotor cortex (PMd) as a priming intervention may modify the long-term potentiation-like (LTP-like) effects of iTBS over primary motor cortex (M1; PMd iTBS-M1 iTBS) in young and older adults. Specifically, PMd iTBS may lower the facilitation of M1 circuits recruited with posterior–anterior (PA) current transcranial magnetic stimulation (TMS; but not AP current TMS) to M1 iTBS in both young and older adults.

This study combines plasma proteomics with an integrated learning model (CatBoost) to develop a longitudinal proteome that has been identified as a reliable biomarker of AD throughout its progression. Subsequently, a plasma protein-based neural network model was developed for stage-specific diagnosis of AD.

The N1 ERP to sounds is suppressed if sounds are self-generated. If such sounds are unexpectedly omitted, an omission N1 ERP is elicited. Here, we test the hypothesis that omission and suppression effects share a common, predictive mechanism. The omission N1 was sensitive to changes in the predictability of sound occurrence, yet the N1 suppression was not. While omission N1 provides evidence for predictive processing, N1 suppression rather relates to unspecific motor related sensory suppression.

Psychedelics changes in perception through serotonin receptor agonism. Effects on the 5HT_2A receptor; neuroplasticity and transcriptomic regulation, as well as specific changes in neural correlates of brain networks. Psychedelic-assisted therapy in disorders such as depression, anxiety and substance use disorders constitutes a strong research area, thus evaluating the clinical use is highly essential (this figure was created with BioRender.com).

Voice attractiveness and social interest significantly influence social decisions on the fairness of proposals for monetary allocations in the Ultimatum Game: The medial frontal negativity in the ERP was enhanced by unfair proposals but only when the proposer's voice was low (L) rather than high (H) attractive or when the spoken message expressed positive (P) rather than negative (N) social interest.