This study shows which treatable traits are present and/or absent in patients diagnosed with ‘asthma’, ‘COPD’ (chronic obstructive pulmonary disease) and ‘asthma + COPD’ in a global, observational study of more than 11,000 patients (NOVELTY), and how their prevalence changes with disease severity.

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Clinical features suggestive of a telomere syndrome are present in a quarter of patients with idiopathic pulmonary fibrosis. These features include a history or family history of haematological or liver disease, or haematological laboratory abnormalities. They are associated with lower leukocyte telomere length and are independently associated with decreased survival.

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This largest case collection of cryotherapy procedures in the paediatric airway to date demonstrates that cryotherapy can be safely and successfully applied for cryobiopsy, restoration of airway patency and foreign body removal. Paediatric interventional bronchoscopists are encouraged to add cryotherapy to their armamentarium of airway interventions in the paediatric airway.

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We studied the combination of atomoxetine and fesoterodine (Ato-Feso), an extended-release anti-muscarinic, on obstructive sleep apnoea (OSA) severity and endotypes. Despite the absence of an effect on OSA severity, Ato-Feso led to improvements in OSA profile, reducing apnoea index and overnight hypoxaemia, especially in patients characterized by low-to-moderate pharyngeal collapsibility.