International Journal of Experimental Pathology: Vol 85, No 1

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International Journal of Experimental Pathology

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International Journal of Experimental Pathology: Volume 85, Issue 1

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BSMB September 2003 Meeting, London

British Society for Matrix Biology Meeting, London, 18–19 September 2003

British Society for Matrix Biology Meeting, London,18—19 September 2003

Current Status Review

Progression and regression in renal vascular and glomerular fibrosis

BSMB September 2003 Meeting, London

Function follows form: how fibronectin matrix architecture controls cell behaviour

The ins and outs of extracellular matrix assembly

Basement membrane and tubular epithelial cell behaviour

Novel mechanisms for regulating the TGF-β-/Smad-signalling pathway

The role of CTGF in mediating the pathogenesis of diabetic nephropathy

Decorin in renal inflammation and fibrosis – more than an inhibitor of TGF-β

Matrix-metabolizing enzymes as prime targets of redox regulation by nitric oxide

The role of chemokines in renal fibrosis

The role of hypoxia in fibrosis

Models and mechanisms of renal epithelial–mesenchymal transdifferentiation

Regulation of epithelial–mesenchymal transformation in vitro

Regulation of PTC phenotype and function by TGF-β1: implications for transdifferentiation

Original Articles

Expression of somatostatin mRNA and peptides in C-cell tumours of the thyroid gland in Han Wistar rats

BSMB September 2003 Meeting, London

Transgenics, knockouts and fibrosis

Smad-3 as a mediator of the fibrotic response

Regulation of inflammation and scarring in glomerulonephritis

Tissue-Transglutaminase and the development of renal fibrosis

Emodin ameliorates glucose-induced fibronectin synthesis in human peritoneal mesothelial cells by inhibiting PKC-α activation

The human hyaluronan synthase genes: putative mediators of renal fibrosis

Bone morphogenetic protein-1 cleaves prodecorin in vitro and in cellulo

The role of acetylation in Timp-1 regulation

Proteomics of tendon ECM assembly

Identification, expression and tissue distribution of the three rat lysyl hydroxylase isoforms

The role of glutamate signalling in rheumatoid arthritis

Discovery of potent and selective inhibitors of procollagen C-proteinase for the treatment of fibrotic disorders

Gene expression and matrix proteinase activity in osteochondrosis dessicans

Novel strategies for enhancing tissue integration in cartilage repair

Effects of n-3 polyunsaturated fatty acids on COX-2 and PGE2 protein levels in articular cartilage chondrocytes

ADAMTS-4 and ADAMTS-5 sequestration and activity in chondrocyte-agarose cultures

Expression profiling of metalloproteinases and inhibitors in cartilage

TGF-β promotes the formation of pyridinoline cross-links in fibrosis via the induction of LH2 expression

Original Articles

Increased oxidative stress and apoptosis in acute puromycin aminonucleoside nephrosis

BSMB September 2003 Meeting, London

TGF-β1 induces epithelial–mesenchymal transition but not myofibroblast transdifferentiation in primary cultures of human epithelial renal tubular cells

Regulation of the small GTPase RhoA by syndecan-4 and integrins in focal adhesion formation

Mesangial matrix-activated mononuclear cells express functional scavenger receptors and accumulate intracellular lipid

Domain deletions outside of the catalytic domain of drosophila tolloid result in loss of protease activity

Decorin affects endothelial cells by interacting with IGF-I and its receptor

NADPH oxidases and MMP-9/TIMP-1 balance in human glomeruli: putative links to diabetic nephropathy

The importance of elastin and fibulin-5 on spine development: a study of elastin KO and fibulin-5 KO on the development of vertebral body and intervertebral disc

Up-regulated lactate, TGF-β and collagen synthesis in the ischaemic skin of patients with peripheral vascular disease

The isoprostane 8-iso-PGF2α suppresses monocyte adhesion to microvascular endothelial cells: a role in limiting inflammation and fibrosis?

Fluorescence lifetime imaging of articular cartilage

Factors affecting oxygen concentration gradients across articular cartilage

A novel keratanase-generated keratan sulphate antibody and its applications

Changes in tendon extracellular matrix composition with age

The role of the cytoskeleton in articular cartilage chondrocyte homeostasis

Original Articles

Evidence of macrophage and lymphocyte, but not dendritic cell, infiltration in posterior uveal melanomas, whilst cultured uveal melanomas demonstrate pluripotency by expressing CD68 and CD163

BSMB September 2003 Meeting, London

PRG-4/SZP N- and C-terminal domains: cloning, expression and characterization

Matrix-degrading enzyme synthesis by cells isolated from the canine cranial cruciate ligament

Controllers of apoptosis in herniated and diseased intervertebral disc

Matrix remodelling in the superficial digital flexor tendon of the horse

Altered patterns of gene expression in endothelial cells in scleroderma

Characterization of the promoter in ADAMTS-5 (aggrecanase-2)

Investigating the PKR-signalling pathway in the articular joint

Identification of cell markers of the nucleus and annulus of bovine intervertebral discs

Type-X collagen interacts with the small leucine-rich proteoglycans decorin and biglycan

Homophilic complex formation is prerequisite for MT1-MMP to degrade type-I collagen on the cell surface

Modulation of the expression of connective tissue growth factor (CTGF) by alterations of the cytoskeleton

Role of the EGF-like domains in mammalian tolloid (mTLD) secretion and procollagen C-proteinase activity

Age-related changes in the glycosaminoglycans of human meniscal aggrecan

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Effects of n-3 polyunsaturated fatty acids on COX-2 and PGE₂ protein levels in articular cartilage chondrocytes

The isoprostane 8-iso-PGF_2α suppresses monocyte adhesion to microvascular endothelial cells: a role in limiting inflammation and fibrosis?