• Issue

    Genes, Chromosomes and Cancer: Volume 50, Issue 12

    969-1084
    December 2011
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Research Articles

Microarray-based genomic profiling as a diagnostic tool in acute lymphoblastic leukemia

Annet Simons,  Marian Stevens-Kroef,  Najat El Idrissi-Zaynoun,  Sabine van Gessel,  Daniel Olde Weghuis,  Eva van den Berg,  Esmé Waanders,  Peter Hoogerbrugge,  Roland Kuiper,  Ad Geurts van Kessel, 
  • Pages: 969-981
  • First Published: 31 August 2011

Molecular profiling reveals frequent gain of MYCN and anaplasia-specific loss of 4q and 14q in wilms tumor

Richard D. Williams,  Reem Al-Saadi,  Rachael Natrajan,  Alan Mackay,  Tasnim Chagtai,  Suzanne Little,  Sandra N. Hing,  Kerry Fenwick,  Alan Ashworth,  Paul Grundy,  James R. Anderson,  Jeffrey S. Dome,  Elizabeth J. Perlman,  Chris Jones,  Kathy Pritchard-Jones, 
  • Pages: 982-995
  • First Published: 31 August 2011

t(4;8)(q27;q24) in Hodgkin lymphoma cells targets phosphodiesterase PDE5A and homeobox gene ZHX2

Stefan Nagel,  Björn Schneider,  Andreas Rosenwald,  Corinna Meyer,  Maren Kaufmann,  Hans G. Drexler,  Roderick A. F. MacLeod, 
  • Pages: 996-1009
  • First Published: 30 August 2011

LOH on 10p14-p15 targets the PFKFB3 gene locus in human glioblastomas

Michael Fleischer,  Renate Kessler,  Angelika Klammer,  Jan-Peter Warnke,  Klaus Eschrich, 
  • Pages: 1010-1020
  • First Published: 30 August 2011

Atypical neurofibromas in neurofibromatosis type 1 are premalignant tumors

Eline Beert,  Hilde Brems,  Bruno Daniëls,  Ivo De Wever,  Frank Van Calenbergh,  Joseph Schoenaers,  Maria Debiec-Rychter,  Olivier Gevaert,  Thomas De Raedt,  Annick Van Den Bruel,  Thomy de Ravel,  Karen Cichowski,  Lan Kluwe,  Victor Mautner,  Raf Sciot,  Eric Legius, 
  • Pages: 1021-1032
  • First Published: 24 August 2011

The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression

Daniel Nettersheim,  Ad Gillis,  Katharina Biermann,  Leendert H.J. Looijenga,  Hubert Schorle, 
  • Pages: 1033-1042
  • First Published: 24 August 2011

Promoter methylation-mediated inactivation of PCDH10 in acute lymphoblastic leukemia contributes to chemotherapy resistance†

Gopeshwar Narayan,  Allen J. Freddy,  Dongxu Xie,  Hema Liyanage,  Lorraine Clark,  Sergey Kisselev,  Ji Un Kang,  Subhadra V. Nandula,  Catherine McGuinn,  Shivakumar Subramaniyam,  Bachir Alobeid,  Prakash Satwani,  David Savage,  Govind Bhagat,  Vundavalli V. Murty, 
  • Pages: 1043-1053
  • First Published: 24 August 2011

A novel EWSR1-CREB3L1 fusion transcript in a case of small cell osteosarcoma†

Larisa V. Debelenko,  Lisa M. McGregor,  Bangalore R. Shivakumar,  Howard D. Dorfman,  Susana C. Raimondi, 
  • Pages: 1054-1062
  • First Published: 24 August 2011

T-cell lymphoblastic lymphoma shows differences and similarities with T-cell acute lymphoblastic leukemia by genomic and gene expression analyses

Katia Basso,  Lara Mussolin,  Antonella Lettieri,  Manisha Brahmachary,  Wei Keat Lim,  Andrea Califano,  Giuseppe Basso,  Andrea Biondi,  Giovanni Cazzaniga,  Angelo Rosolen, 
  • Pages: 1063-1075
  • First Published: 30 August 2011

Genome-wide linkage analysis of Swedish families to identify putative susceptibility loci for cutaneous malignant melanoma†

Veronica Höiom,  Rainer Tuominen,  Johan Hansson, 
  • Pages: 1076-1084
  • First Published: 07 September 2011