International Journal for Numerical Methods in Biomedical Engineering

This study analyzed and compared the mechanical function of bone scaffolds under various conditions using the computational approach. Bone scaffolds play a crucial role in replacing damaged bone, supporting external loads, and transmitting mechanical stimuli to adjacent tissue. However, designing bone supports based solely on high apparent elastic moduli reduces their ability to transfer loads to the surrounding bone tissue. In contrast, a bone scaffold with an apparent elastic modulus similar to that of the adjacent bone at the implantation site ensures effective load transfer and structural support.

This figure illustrates the newly proposed visco-hyperelastic material model for spinal ligaments under dynamic loads. It highlights both the Neo-Hookean matrix and transversely isotropic fibers, enhanced by viscous terms. The model is supplemented by an IIR filter to eliminate numerical oscillations at high strain rates, ensuring stable and accurate FEM simulations.

The parameterized cross-sectional model allows assessment of the effect of geometric variability in iliac atherosclerotic arteries during angioplasty balloon inflation. The size of the lipid pool and the thickness of the fibrous cap primarily control, respectively, the magnitude and location of the maximum principal stress in the artery. Our study highlights the importance of using a parameterized finite element model over deterministic approaches.