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![[Figure 8]](https://journals.iucr.org/gm5092fig8mag.jpg)
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| Figure 8 Views of the active site of SARS-CoV-2 Mpro in complex with ABT-957 (a) under cryogenic conditions (Redhead et al., 2021  ) and (b) at room temperature. Contours for the ligand density are drawn at 3σ. (c, d) Two slightly displaced views of the active site of SARS-CoV-2 Mpro in complex with ABT-957 to show the conformational differences observed, particularly
for the oxopyrrolidine and benzyl moieties of ABT-957 when bound to Mpro, at cryo temperature (cyan) and room temperature (green). The structures were superimposed
using PyMOL (Schrödinger) |
![[Figure 8]](https://journals.iucr.org/10.1107/S2059798322004399/gm5092fig8.jpg)
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STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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