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Figure 5
Pairwise structural alignments of each chain of the ADP-bound structure (PDB entry 9i51; wheat) were performed against the corresponding chains of the apo-form (PDB entry 7nio; green), phosphate-bound (PDB entry 9i4v; blue) and AMP-PNP-bound (PDB entry 7nn0; yellow) structures of SARS-CoV-2 NSP13. NSP13 is shown in cartoon format. Nucleotides and phosphates are depicted in ball-and-stick format, coloured to match the respective proteins, while interacting residues are shown in stick format. The following alignments are illustrated: (a) chain A of the ADP-bound structure with chain E of the apo form, (b) chain B of the ADP-bound structure with chain A of the apo form, (c) chain A of the ADP-bound structure with chain A of the phosphate-bound structure, (d) chain B of the ADP-bound structure with chain B of the phosphate-bound structure, (e) chain A of the ADP-bound structure with chain B of the AMP-PNP-bound structure and (f) chain B of the ADP-bound structure with chain D of the AMP-PNP-bound structure.

Journal logo STRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 81| Part 8| August 2025| Pages 338-347
https://doi.org/10.1107/S2053230X25005266
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