When is ‘intersex’ not intersex? A case of penile agenesis demonstrates how to distinguish non-endocrine disorders in neonates with genital anomaly
J Srinivasan, P McDougall, JM Hutson,
JM Hutson
Department of General Surgery,
Centre for Early Sexual Development, Royal Children's Hospital,
Murdoch Childrens Research Institute and
Department of Paediatrics, University of Melbourne, Victoria, Australia
Search for more papers by this authorJ Srinivasan, P McDougall, JM Hutson,
JM Hutson
Department of General Surgery,
Centre for Early Sexual Development, Royal Children's Hospital,
Murdoch Childrens Research Institute and
Department of Paediatrics, University of Melbourne, Victoria, Australia
Search for more papers by this authorProfessor JM Hutson, Department of General Surgery, Royal Children's Hospital, Parkville, Vic. 3052, Australia. Fax: +61 3 9345 7997; email: [email protected]
References
- 1 Stephens FD, Smith ED, Hutson JM. Congenital Anomalies of the Kidney, Urinary and Genital Tracts, 2nd edn. Martin Dunitz, London, 2002.
- 2 Clarnette TD, Sugita Y, Hutson JM. Genital anomalies in the human and animal models reveal the mechanisms and hormones governing testicular descent. Br. J. Urol. 1997; 79: 99−112.
- 3
Beasley SW,
Hutson JM,
Howat AJ,
Kelly JH.
Posterior ectopia of penis mimics marsupial anatomy. Case reported in association with a primitive cloacal anomaly.
Pediatr. Surg. Int.
1987;
2: 127−30.
10.1007/BF00174192 Google Scholar
- 4
Evans JA,
Erdile LB,
Greenberg CR,
Chudley AE.
Agenesis of the penis: patterns of associated malformations.
Am. J. Med. Genet.
1999;
84: 47−55.
10.1002/(SICI)1096-8628(19990507)84:1<47::AID-AJMG10>3.0.CO;2-X CAS PubMed Web of Science® Google Scholar
- 5 Aspiroz J. Agenesis of the penis. J. Pediatr. Surg. 1971; 6: 74.
- 6 Young H, Cockett ATK, Stoller R, Ashley F, Goodwin WE. The management of agenesis of the phallus. Pediatrics 1971; 47: 81−7.
- 7 Lisa L, Hanak J, Cerny M, Faflova H, Kafka V, Braza J. Agenesis of the penis. J. Pediatr. Surg. 1973; 8: 327−8.
- 8 Koffler H, Aase JM, Papile L, Coen RL. Persistent cloaca with absent penis and anal atresia in one of identical twins. J. Pediatr. 1978; 93: 821−3.
- 9 Gautier T, Salient J, Pena S, Imperato-McGinley J, Peterson RE. Testicular function in 2 cases of penile agenesis. J. Urol. 1981; 126: 556−7.
- 10 Oesch PL, Pinter A, Ransley PG. Penile agenesis: a report of six cases. J. Pediatr. Surg. 1987; 22: 172−4.
- 11 Gilbert J, Clark RD, Koyle MA. Penile agenesis: a fatal variation of an uncommon lesion. J. Urol. 1990; 143: 338−9.
- 12 Gluer S, Fuchs J, Mildenberger H. Diagnosis and current management of penile agenesis. J. Pediatr. Surg. 1998; 33: 628−31.
- 13 Wittkopf JE, Cooper CS, Hawtrey CE. Penile agenesis with a separated scrotum and normal renal function in an identical twin. J. Urol. 2002; 167: 687−8.
- 14 Lerman SE, McAleer IM, Kaplan GW. Sex assignment in cases of ambiguous genitalia and its outcome. Urology 2000; 55: 8−12.
- 15 Dittman RW. Ambiguous genitalia, gender-identity problems, and sex reassignment. J. Sex Marital Ther. 1998; 24: 255−71.
- 16 Hrabovszky Z, Hutson JM. Androgen imprinting of the brain in animal models and humans with intersex disorders: review and recommendations. J.Urol. 2002; 168: 1751−3.
- 17 Kaefer M, Adams MC. Penis and bladder agenesis in a living male neonate. J. Urol. 1997; 157: 1439−40.
- 18 Ciftci AO, Senocak ME, Buyukpamukcu N. Male gender assignment in penile agenesis: a case report and review of the literature. J. Pediatr. Surg. 1995; 30: 1358−60.
- 19 Bruch SW, Meuli M, Harrison MR. Immediate reconstruction for penile agenesis. J. Pediatr. Surg. 1996; 31: 1152−4.
- 20 Wittkopf JE, Cooper CS, Hawtrey CE. Penile agenesis with a separated scrotum and normal renal function in an identical twin. J. Urol. 2002; 167: 687−8.
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