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RETRACTED: Artificial intelligence for emergency medical care

Shivam Rajput

Shivam Rajput

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India

Contribution: Methodology (equal), Resources (equal), Writing - original draft (equal)

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Pramod Kumar Sharma

Pramod Kumar Sharma

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India

Contribution: Data curation (equal), Project administration (equal), Resources (equal)

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Rishabha Malviya

Corresponding Author

Rishabha Malviya

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India

Correspondence Rishabha Malviya, Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh, India.

Email: [email protected] and [email protected]

Contribution: Formal analysis (equal), Supervision (equal), Writing - review & editing (equal)

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First published: 13 October 2023
Citations: 3

Abstract

There is increasing research into the potential benefits of incorporating artificial intelligence (AI) and machine learning algorithms into emergency medical services. AI is finding new applications across a wide range of sectors, one of which is healthcare, where it is being used to enhance clinical diagnostics. AI solutions have enormous untapped potential to improve healthcare efficiency and quality, thus researchers have focused heavily on emergency medicine (EM). Many individuals without prior experience with any physician often receive their initial medical care in the emergency room. Two areas that could benefit from the implementation of AI are reducing waiting times and enhancing diagnostic capabilities. This study provides further explanation of how AI is used in emergency rooms. Several machine learning-based algorithms are also addressed. In this research, we summarise recent developments in the use of AI in EM. This research tries to summarise the usefulness of AI in EM by looking at recent developments in emergency department operations and clinical patient management.

Abbreviations

  • AI
  • artificial intelligence
  • ANNs
  • artificial neural networks
  • ARIMA
  • autoregressive integrated moving average
  • AUC
  • area under curve
  • AUROC
  • area under the receiver operating characteristic curve
  • COPD
  • chronic obstructive pulmonary disease
  • CT
  • computed tomography
  • DT
  • decision tree
  • ED
  • emergency department
  • EEMD
  • ensemble empirical mode decomposition
  • EM
  • emergency medicine
  • EMT
  • emergency medical technician
  • ER
  • emergency room
  • ESI
  • Emergency Severity Index
  • EWS
  • early warning system
  • GBM
  • gradient-boosted machines
  • K-NN
  • K-nearest neighbour
  • KTAS
  • Korean Triage and Acuity Scale
  • LINR
  • linear interval model and regression analysis
  • LSTM
  • long short-term memory
  • ML
  • machine learning
  • MLP
  • multilayer perceptron
  • MSE
  • mean squared error
  • NEDIS
  • National Emergency Department Information System
  • NLP
  • natural language processing
  • OHCA
  • out-of-hospital cardiac arrest
  • RBN
  • radial basis network
  • RC
  • random blend choice
  • RF
  • random forest
  • RI
  • random input
  • RMA
  • regional moving average
  • SARIMA
  • seasonal autoregressive integrated moving average
  • SMART
  • scalable medical alert response technology
  • SOAP
  • subjective, objective, assessment and plan
  • SVM
  • support vector machine
  • SVR
  • support vector regression
  • XGBoost
  • extreme gradient boosting
  • 1 INTRODUCTION

    With almost unlimited potential for bettering patient care and optimising the healthcare system, artificial intelligence (AI) may be the next significant technological advance to alter healthcare delivery [1]. The fundamental principle underlying AI, machine learning (ML) and deep learning, as per the scholarly discourse, involves the integration of human intelligence into computer systems, despite the diverse definitions and interpretations put forth by scholars over time. AI is a subfield of computer science that aims to give computers the ability to learn and perform tasks often associated with human intelligence. This all-encompassing description does a good job of describing AI; its subfields, ML and deep learning, are methods used to teach computers to behave like humans in a variety of contexts, including recognising patterns in data and drawing inferences from them. The term ‘machine learning’ is used to describe the process by which computers can ‘learn’ to perform better over time without being expressly programmed to do so. ML uses algorithms to analyse and predict outcomes based on a set of features provided by the user. The model is trained using structured data that highlights the specific features of a data set, and is subsequently used for inference. Supervised and unsupervised learning aim to establish connections between inputs and outputs. However, deep learning utilises a complex network of nodes to enhance its algorithms' ability to effectively address complex problems [2]. Deep learning utilises artificial neural networks (ANNs) to model the functionality of biological neurons in the human brain. Automatic feature definitions are extracted at several phases to provide low, medium and high levels of representation as inputs for learning. In contrast to conventional computerised tools that operate based on pre-established human hypotheses, ML and deep learning algorithms acquire knowledge by autonomously generating and validating assumptions derived from the analysis of extensive data sets [3]. During the learning process, features are created by nonlinearly converting the initial data at every input layer node. These attributes, each with its own weight in relation to neighbouring nodes, are added up and used as inputs in the subsequent layer. The inference is made at the end of the chain, in the output layer. To train a neural network, the input data is repeatedly passed through the network, allowing the density of the neurons to be adjusted. Backpropagation employs methods such as gradient descent to minimise the cost function, which represents the discrepancy between the predicted and observed values. The adornments serve as evident indications of practical knowledge acquisition [4, 5].

    As per the American College of Emergency Physicians, the field of emergency medicine (EM) pertains to the specialised branch of medicine that is focused on the identification and management of unforeseen medical conditions or injuries. Doctors and nurses in the emergency room (ER) must quickly analyse, diagnose, cure and stabilise patients with a wide range of medical conditions. Rapid medical assessment, recovery, therapy and stability of the patient are essential [6]. The distinctive obstacles posed by the field of EM have positioned it as a prominent topic of discussion in regard to the implementation of AI within the healthcare industry. The field of emergency care is currently experiencing a surge in departmental flow issues and a demand for prompt and accurate decision-making for patients with severe injuries [7]. Given these circumstances, the potential benefits that AI technology could offer in terms of enhanced speed and precision are of great interest. Indeed, Emergency Departments (EDs) represent the primary and most established domains where AI has been implemented in the field of EM. The potential of AI has been demonstrated in the interpretation of diagnostic imaging, prognostication of patient outcomes and monitoring of vital signs such as pulse, temperature, blood pressure and respiration tracking. In addition, several enterprises are currently engaged in the development of AI systems that utilise natural language processing (NLP) techniques to generate patient charts in real time based on audio recordings of doctor–patient consultations [8, 9]. Several new projects, such as home monitoring programmes and disease spread prediction systems, attempt to take AI beyond the ER and the hospital [10]. Although AI could potentially benefit many areas of healthcare, it has not been widely embraced at either the departmental level (such as the ER) or the systemic level (hospitals and health systems). This is due in part to contextual differences and the availability of competing AI-based solutions, among other things.

    The primary difficulty in EM is ensuring the prompt delivery of medical triage, which involves categorising patients based on their level of urgency and severity. This requirement arises from the unpredictable nature of emergencies and the presence of limited and stretched resources, such as staffing and beds. ML and deep learning have the potential to analyse historical data patterns and provide valuable insights for enhancing ED processes. ML has the potential to support ongoing medical trials and research by leveraging its inherent strengths in areas such as data pattern and trend recognition, image analysis and classification tasks. This can lead to decreased workloads for medical professionals involved in these studies. This paper reviews ML and deep learning techniques used in EM and their impact on healthcare quality improvement.

    2 ML'S IMPORTANCE IN THE FIELD OF EM

    The utilisation of ML algorithms has the potential to enhance disease prediction and identification within the ED, ultimately resulting in improved patient outcomes, reduced side effects and decreased healthcare costs. An increase in the number of patients admitted to the ED would lead to longer waiting times and decreased efficiency of medical staff. Thus, the employment of AI and ML approaches in the ED may lead to improved administration, enhanced resource allocation and faster patient discharge.

    3 VARIOUS KIND OF ML TECHNIQUES

    ML is a subfield of AI that endows computational systems with the capacity to identify and adjust to novel circumstances. When it comes down to it, ML is nothing more than a collection of methods and algorithms that can predict events or classify data based on spotting patterns in the available data. Several significant techniques are utilised in this domain, such as Support Vector Machine (SVM), the Naive Bayes algorithm, K-Nearest Neighbour (K-NN), Decision Tree (DT), Random Forest (RF) and the Ensemble model. ML algorithms are now widely used. Depending on how they learn (supervised, unsupervised or semisupervised learning, respectively), these are categorised in one of three ways.

    3.1 Supervised learning

    The model is trained with the help of an identified data set. The inputs produce the outputs. The present model involves the organisation and division of data into distinct subsets, namely a training set and a testing set. The model is trained using the training data set, and its accuracy is evaluated using the testing data set. The data set incorporates both models and their corresponding outcomes. This technique is frequently applied in classification and regression scenarios [11]. Classification algorithms are commonly utilised in supervised learning methods to ascertain the probability of disease development [12].

    3.2 Unsupervised learning

    It is not possible to classify or categorise training data within the data set itself. The purpose is to unearth previously unseen relationships within the data. To develop patterns, the model is trained. It can rapidly and correctly find hidden patterns in each new input data set, but it needs to study the data to draw inferences and characterise those patterns. When using this method, one gets no hits on the data set [13].

    3.3 Reinforcement learning

    There is no labelled data set used, and no data associations are made, so the model simply uses past data to improve itself. This technique enables the model to address its flaws, adjust its presentation based on its environment and ultimately determine the optimal outcome through the evaluation of different options.

    4 ML-BASED ALGORITHM

    The following section will explain various ML-based algorithms that are utilised in the field of healthcare.

    4.1 Nave Bayes classifiers

    Nave Bayes, a classification technique based on Bayes' Theorem, is known for being both simple to understand and accurate in practice. The theorem of Bayes simplifies categorisation. It implies a strong (naive) independence trait. The assumption is that the predictors are unrelated, meaning that the traits or characteristics are also not correlated. It is called ‘naive’ because each of these qualities or characteristics still has its own effect on the probability, even when there is reliance. The theorem of Bayes calculates probability. Predictors have no relationship or correlation. All attributes maximise their probability independently. It employs the Naive Bayes model without the use of Bayesian procedures. Naive Bayes classifiers are necessary for complex real-world situations [14].
    ()

    In Equation 1, P(Y/X) represents the posterior probability, P(X) represents the class prior probability and P(Y) represents the predictors prior probability, also known as the likelihood. Naive Bayes is a powerful classification method that works well with nonlinear and complicated data, but its predictive value is reduced since it depends on assumptions and class-conditional independence.

    4.2 SVM

    The SVM is a prevalent technique in supervised ML used for the classification and prediction of data with a predetermined target variable. The process involves identifying a hyperplane within the feature space that effectively separates the classes. The SVM model aims to maximise the distance between points belonging to different classes when projected onto a feature space. Data from the test is predicted in this space and then classified according to whether it falls inside or outside the border (Figure 1) [15].

    Details are in the caption following the image
    Diagrammatic representation of a support vector machine.

    4.3 DT

    One type of supervised learning algorithm is the DT. The primary application of this method is solving categorisation issues. It works wonderfully with both continuous and categorical data. This algorithm takes the most important predictors and uses them to split the population into two or more groups with similar characteristics. When it comes to classifying data, a DT can be utilised for either numerical or categorical classification. The DT is a diagramming instrument in the form of a tree. Because of their usefulness and simplicity, DTs have found significant usage in the area of EM [16]. To begin, the DT algorithm determines the entropy of every attribute. In the next step, the variables or predictors that provide the greatest information gain or the least entropy are used to partition the data set. To process the remaining attributes, these two processes are repeated in a recursive fashion. A tree-like graph can be quickly implemented and analysed with little effort (Figure 2). Three nodes are used in the analysis performed by the DT model.

    • (a)

      Root node: The root node is the source of all other nodes' abilities.

    • (b)

      Interior node: manipulates a wide range of attributes and characteristics.

    • (c)

      Leaf node: conform to the results of the individual tests.

    Details are in the caption following the image
    Diagrammatic representation of decision tree.
    The data is partitioned into two or more sets that are comparable based on the variables that have the most importance in the analysis. The entropy of each characteristic is computed, and the data is then split into predictors based on whether they yield the greatest information gain or the least:
    ()
    In Equation 2, is simply the frequentist probability of an element/class ‘’ in data. For simplicity's sake, let us say there are only two classes: positive and negative. Therefore, ‘’ here could be either + or (−). So, if there are a total of 100 data points in a data set with 30 belonging to the positive class and 70 belonging to the negative class then ‘P+’ would be 3/10 and ‘P−’ would be 7/10. Pretty straightforward.
    ()

    In Equation 3, the is the set of all possible values for attribute , and is the subset of for which attribute A has value v. Note the first term in the equation is just entropy of the original sample , and the second term is the expected value of entropy after is partitioned using attribute . Expected entropy described by this second term is simply the sum of entropies of each subset , weighted by the fraction of examples that belong to . is, therefore, the expected reduction in entropy caused by knowing the value of attribute .

    The outcomes are more readable and understandable. Since it examines the data set in a tree-like graph, this technique is more precise than its competitors. However, only one attribute is ever put to the test in a judgement, and the data may have been over-classified [17].

    4.4 K-NN

    One type of supervised classification algorithm is the K-NN algorithm. It uses nearest-neighbour relationships to put things into categories. Instance-based learning is the kind that this falls under. The K-NN rule, developed by researchers in 1951, is a nonparametric method for classifying patterns. It is one of the simplest classification methods, but the K-NN methodology is quite powerful. K's nearest neighbour has a Euclidean distance. Euclidean distance is used to determine how far apart two attributes are in a set [18]. It is used for classification problems where prior knowledge of the data distribution is minimal, if not nonexistent, and no assumptions are made about the data. The mean of the k most comparable data points from the training set is used to replace a missing target value in this method. It does it by consulting a list of labelled locations for guidance on where to place yet another dot. K-NN may be used to infer missing values by grouping observations into clusters according to their similarities. When the blanks are filled in, the data set can be used with a variety of prediction methods. Combinations of these algorithms can be used to improve precision.

    4.5 Ensemble model

    Analytical data from two or more similar but distinct models are integrated with ensemble modelling to form a single score. Ensemble methods in ML aim to construct a singular predictive model that outperforms the individual results of the underlying models as depicted in Figure 3 [19].

    Details are in the caption following the image
    Diagrammatic representation of Ensemble model.

    4.6 RF algorithm

    This algorithm is another supervised ML method. Even though this method is effective in both regression and classification settings, it shines in the latter. The output of the RF approach is a synthesis of many different DTs, as the name suggests. Several trees work together to form a forest in this procedure. In an RF, each tree emits an expectation about a class, and the most popular class is used to inform the model's prediction. Thus, it can be thought of as a collection of different kinds of DTs. The theory behind this method is that a larger sample size will eventually yield a reliable result. A voting method is used to determine the class, while the average of the DTs' predictions is used for regression. It is capable of handling high-dimensional and large data sets without difficulty [20]. An RF classifier employs more trees to improve its accuracy (Figure 4).

    Details are in the caption following the image
    Diagrammatic representation of random forest algorithm.

    The three most common methods are as follows:

    • (a)

      Forest RI (random input);

    • (b)

      Forest RC (random blend choice);

    • (c)

      Combination of forest RI and forest RC.

    It is utilised for classification in addition to regression, and due to its capacity to account for missing information, it is particularly useful for classification. Predictions are difficult to obtain since more data and more trees are needed, and the process is time-consuming. Excellent results can be obtained using RFs [21].

    5 THE URGENT NEED FOR AI IN EM

    Medical triage, or the process of categorising patients into groups based on their level of urgency and seriousness, is the major challenge of EM. This is necessary because emergencies and the conditions surrounding them are unpredictable, and because resources (such as staffing and beds) are sometimes restricted and stretched [22, 23]. Research has shown that an elevated number of patients in ER might negatively impact healthcare quality. Furthermore, such incidences are linked to increased mortality [24-26]. ML and deep learning have the potential to assist ED personnel in making more precise decisions by enabling the interpretation of data gathered over a period. The tool possesses inherent strengths in various areas, such as information pattern and trend recognition, picture evaluation and categorisation activities and decreased workloads for medical professionals involved in ongoing medical trials and research. As a result, it is considered an asset in these fields [27, 28]. The increasing utilisation of this technology in various medical domains, including but not limited to cancer and radiology, has enabled its potential to generate highly precise prognoses and diagnoses in the absence of medical practitioners [29-32]. The use of AI to create personalised therapy regimens for each patient has the potential to improve health outcomes [33]. Following is a discussion of the role and various applications of AI in EM and how these applications affect the quality of patient care. Typical ED patient treatment is shown in Figure 5.

    Details are in the caption following the image
    A standard process flowchart for emergency department cases.

    6 THE SIGNIFICANCE/MECHANISM OF AI IN EM

    The following section will explain the workflow of AI in EM.

    6.1 AI-based predictive modelling

    Predictive modelling is a logical fit for AI in the medical field. Disease and other unfavourable consequences can be predicted by a wide variety of AI systems. Particular attention has been paid to the use of AI for making predictions in the field of emergency care. DTs, Logistic regression (LR) and gradient-boosted machines (GBM) were some of the AI techniques and data mining methods employed by researchers to forecast hospital admissions using ED data [34]. One study reports the development of a web-based application that utilises various techniques of data mining and ML to provide real-time estimations of the likelihood of a future visit to the ED [35]. The present research has exhibited the potential utility of data derived from nonhospital settings, such as outpatient clinics, in enabling population-level risk assessments, with AI assuming a pivotal role. A clinical decision tool was introduced by researchers with the aim of predicting the patients who are likely to require readmission to the ED within 72 h [36]. Using patient-specific data, ED staff and administration may be able to predict whether a patient would be readmitted to the ED within 72 h, giving them a window of opportunity to improve care and give further instruction to reduce ED readmissions.

    ANNs represent a prevalent category of AI techniques and algorithms. In a study conducted by researchers, it was demonstrated that the behaviour of infants and toddlers with bronchiolitis can be predicted through the utilisation of ANN ensembles [37]. However, an accurate estimation of the duration of the patient's hospitalisation was not achieved. A model based on ANN was developed by researchers to predict injuries in the craniocervical junction of patients who have suffered trauma [38]. With data collected in the ER, researchers also proposed a model to predict the occurrence of acute coronary syndromes [39]. In the pursuit of forecasting mortality and acute morbidity, a total of 17 statistical and AI techniques, such as neural networks, were utilised to construct models [40]. In a study conducted by scholars, ANNs were employed in conjunction with genetic algorithms, a metaheuristic approach inspired by natural selection, to forecast renal colic in high-risk scenarios [41].

    The advent of electronic health records has facilitated the feasibility of predictive modelling for intricate and extensive data sets. However, traditional LR becomes difficult when there are higher variables that are independent than observations [42]. An efficient and practical solution to this issue is variable selection. In their study, the researchers employed a ranking technique to identify a specific set of characteristics that could be utilised to forecast the incidence of severe adverse cardiac events among patients with chest pain who visit the ED [43]. This subset was found to be as predictive as the whole set of variables. This study demonstrated the efficacy of ML and AI over clinical evaluations for forecasting in-hospital mortality for ED patients with sepsis by ranking parameters according to their determined importance [44].

    6.2 AI-based patient monitoring

    The continuous gathering and analysis of massive amounts of patient physiological data are no longer science fiction thanks to advances in sensor technology and the proliferation of computational capacity. The research group demonstrated a wireless, integrated system for monitoring patients in the ED who are unattended [45]. The present investigation examined the efficacy of a prototype of the scalable medical alert response technology system within a limited scope. The authors of a recent study have created and extensively assessed an integrated system for monitoring patients in the ED [46]. There was a network of Personal Digital Assistants and bedside monitors that talked to the unified system. The researchers compared and evaluated a traditional, individually constructed Early Warning System (EWS) with an EWS based on an AI system. The study of considerable scope also examined the efficacy of automated techniques for assessing patients through the utilisation of pre-existing electronic health records and AI-based methodologies. Clinical decision support often benefits from the integration of AI characteristics into interdisciplinary patient monitoring systems. Previous studies have explored the utilisation of AI tools in managing physiological data, such as electrocardiography, within emergency contexts [47, 48].

    6.3 AI-based ED operations

    The effective management of resources and patient flow are essential duties of the ED. In a study, researchers predicted ED workload using a time series analytic method called autoregressive integrated moving average (ARIMA) [49]. Evidence from their study supported the application of forecasting models to the scheduling and allocation of personnel and other resources. To evaluate the effect of different physician staffing arrangements on ED crowding, researchers created an agent-based simulation programme [50]. One hospital's ER has tested the effectiveness of such a device.

    To properly triage patients in the ED, diagnostic decision support systems are required. The proposed diagnostic modelling technique in research has the potential to facilitate the faster generation of diagnostic decision support applications [51]. Once the technology has been tried and evaluated in the ED and found to be effective, it can be used in other settings. Similar data mining approaches were employed by researchers to aid in making diagnoses in a paediatric ER [52].

    In addition, AI and ML methods are now routinely incorporated into ED procedures. In a study conducted by researchers in the field of research, various data mining techniques, such as Naive Bayes and the C4.5 algorithm, were utilised to assess the degree of severity of patients in the ER [53]. In a study conducted by researchers, ML techniques were employed to make predictions regarding the positions of ED staff in relation to the triage of patients diagnosed with asthma and chronic obstructive pulmonary disease [54]. Researchers proposed the automation of outcome categorisation of ED computed tomography reports for adult and paediatric patients through the utilisation of NLP and ML algorithms [55, 56]. Another study employed NLP to develop an algorithmic framework for subjective, objective, assessment and plan analysis of ED reports [57].

    7 THE UTILISATION OF AI IN EM

    The following section will explain how AI can be utilised in the EM field.

    7.1 Prehospital emergency management

    Patients who have called for emergency medical technician assistance but have not yet arrived at the hospital may have received prehospital EM [58]. The utilisation of machine and deep learning methodologies in this domain holds promise for accomplishing two objectives: (1) detecting ailments that demand prompt medical intervention and (2) predicting exigent circumstances that call for advanced preparation and allocation of resources before the patient's admission.

    In a study conducted by researchers, a deep learning algorithm was created to forecast the requirement of critical care in similar situations [59]. This algorithm enabled more accurate patient categorisation and expedited transportation to ERs equipped with the necessary medical resources. The researchers utilised data from the Korean National Emergency Department information system (NEDIS) to train a feed-forward neural network consisting of five hidden layers and 89 nodes. The predictive model utilised sex, age, significant medical concerns, duration from symptom onset to arrival, trauma and initial vital signs to accurately forecast the requirement for critical care, exhibiting a noteworthy area under the receiver operating characteristic curve (area under curve [AUC]) of 0.867. The effectiveness and adaptability of deep learning in triage prediction is evidenced by its performance in comparison to other triage algorithms, namely the Emergency Severity Index (ESI) (0.839), the National Early Warning Scores (EWS) (0.741), the Modified EWS (0.696) and the Korean Triage and Acuity System (0.824).

    In a study conducted by researchers, an ML framework called Corti.ai was utilised to analyse audio recordings from emergency dispatch calls [60]. The objective was to detect and classify instances of out-of-hospital cardiac arrest (OHCA). The audio recordings were segregated into two distinct categories based on the presence or absence of OHCA. K-fold cross-validation was employed to facilitate the training process. The study involved 918 cases of OHCA, wherein an ML framework and a human medical dispatcher were compared in terms of their ability to accurately identify OHCA cases. Results showed that the ML framework had a significantly higher accuracy rate of 84.1% (p = 0.001) compared to the human medical dispatcher's accuracy rate of 72.4%. The framework that underwent training exhibited a 1.1% error rate, having missed solely 10 calls out of the entire set. In comparison to the median time of 54 s for human detection, the ML framework exhibited a median detection time of 44 s for OHCA.

    In a study conducted by researchers, the RF approach was utilised to rank 16 characteristics that are associated with the 30-day survival rate following OHCA [61]. This study investigated the relative importance of individuals with a shockable rhythm, individuals without a shockable rhythm and the overall population. The results offer novel perspectives on the predictability of initial rhythm, age, time elapsed before cardiopulmonary resuscitation was administered, duration of emergency medical services' arrival and the exact site of cardiac arrest, while downplaying the importance of other variables such as gender and time of cardiac arrest. The findings of this study indicate the imperative need for prehospital and ED medical readiness, alongside further investigation into mortality rates and suitable interventions.

    In a study conducted by researchers, various ML methods were assessed using genuine ambulatory and demographic data sets to enhance the accuracy of ambulance demand predictions [62]. This is a crucial metric for prehospital emergency service providers and EDs, as it enables them to prepare, deploy and provide optimal care for the individuals they serve. The intricate nature of the multifaceted components and the nonlinear dynamics associated with the demand for emergency services pose significant challenges in achieving precise predictions of this nature. The study employed multiple data sets, comprising demand history, geographic locations and demographic data, to assess the performance of six distinct ML classifiers. The five models under consideration are the Regional Moving Average (RMA), Support Vector Regression (SVR), Linear Interval Model and Regression Analysis (LINR), Multilayer Perceptron (MLP) and Radial Basis Network. The findings of the comparisons indicate that LightGBM not only outperforms other models but also highlights the significance of incorporating total demand data from the preceding 7 and 30 days to achieve accurate predictions of future demand.

    7.2 Seriousness, classification and treatment of patients

    Medical personnel can use machine as well as deep learning methods to help them determine the severity of a patient's condition and whether they need nursing care [63, 64]. Disposition is the next step for a patient based on their clinical outcomes, therefore, this is also related.

    We begin by talking about the AI methods that are utilised for assessing and prioritising patients. Researchers found that an RF-based ML electronic triage solution outperformed the US ESI in terms of performance [65]. It was especially useful for refining and identifying patients at the third-highest ESI level. Over 14,326 ESI Level three patients (around 10% sampled) were found to require higher levels of care as a result of the implementation's testing in multiple EDs. This demonstrated the usefulness of the created e-triage tool and brought to light the need for enhancements to the existing techniques of categorising triage.

    Multiple ML models were created and analysed by researchers to see if they could be used to reliably predict KTAS scores [66]. The study employed structured clinical data and unstructured free-form texts to train three distinct ML models, namely recurrent fusion, LR and extreme gradient boosting (XGBoost). The RF and XGBoost models exhibited superior performance in comparison to models constructed solely on clinical data (AUROC 95% confidence interval [CI], 0.913, 0.912, 0.905). This finding highlights the intricate nonlinear associations that underpin structured data. It is noteworthy that the LR model outperformed the models that were solely trained on clinical data, with an area under the receiver operating characteristic curve (AUROC) of 0.905 and a 95% CI.

    Professionals developed a deep learning triage and acuity score in a research study, utilising a five-layer MLP model [67]. The individuals who were part of the study were hospitalised patients with high risk, necessitating intensive care and hospitalisation. This study utilised data from the Korean NEDIS to analyse the medical records of 11,656,559 patients who received treatment at 151 EDs throughout Korea. The study focused on the input characteristics that were necessary for triage, including gender, age, symptoms, time elapsed between symptom onset and ED visit, mode of arrival, injuries, initial vital signs and mental status. These input characteristics were found to be sufficient for triage purposes, in contrast to the intricate scoring methods and information requirements of conventional triage tools. The versatility of the concept is underscored, as it can be implemented across diverse contexts, such as prehospital emergency medical services.

    A system was developed by researchers that utilises the initial nursing assessment to predict adverse clinical outcomes such as fatality or emergency admission. This approach is like the one employed by previous researchers, who utilised machine and deep learning techniques to improve existing emergency systems [68]. The results indicate that the performance of LR is comparable to that of neural networks, provided that the dimensionality of the data set is kept low.

    In a study conducted by researchers, a web-based interface was created utilising machine and deep learning technology to establish a correlation between acute stomach discomfort and an ESI score [69] Six distinct baseline models were evaluated, and then those results were used as inputs for a larger ensemble of models. The AUC values increased, indicating a higher degree of accuracy.

    In research where AI was applied to predict outcomes, researchers employed ML to determine the most crucial patient symptom requirements for hospital admissions [70]. To forecast hospital admissions based on patient medical records and triage factors, researchers compared nine machine and deep learning algorithms [71]. It shows without a reasonable doubt that AI can accurately foretell patient admission to a hospital.

    For predicting paediatric ED admissions in real-time using deep neural networks a study was conducted to compare and evaluate organised and unstructured triage text data [72]. The addition of textual information increased AUC by 1.9%. Once again, this demonstrates the significance of including textual data in models.

    A method for creating EWS models using ensembles of DTs was proposed by researchers [73]. In the past, EWS models have relied on clinicians' best judgement to build and be fine-tuned through tentacles' iterative optimisation to identify potential dangers. The purpose of the proposed protocol is to speed up the process of creating low-cost EWS models and to aid in comparing and validating those that already exist in terms of criteria like prediction performance and feature prioritisation.

    7.3 Diagnosis and prognosis of health problems

    ML and deep neural networks are being used to improve medical diagnosis. In some cases, access to specialists with board certification may be limited. After regular business hours or in nations with a dearth of skilled specialists, this is especially relevant [74-76]. As a result, some patients may receive care from medical professionals who lack expertise in treating their specific illnesses. The implementation of machine and deep learning models has the potential to serve as a viable alternative to address the limited availability of medical specialists.

    The prevalence of pain as a primary symptom in patients has prompted researchers to assess the efficacy of machine and deep learning algorithms in identifying and classifying patients into two distinct binary categories, namely those experiencing pain and those who are not, by analysing unstructured text sections in electronic health records [77]. The study yielded a noteworthy outcome in the form of a macro-average F1 score, which is a commonly used metric for assessing classification tasks. The score was recorded at 90.96%, thus demonstrating the efficacy of the AI employed in the study. The study utilised unstructured ED reports to evaluate the performance of various ML classifiers in detecting influenza [78]. The objective of this study was to ascertain the temporal and spatial occurrences of atypical emergency incidents. A total of 31,268 ED records from four hospitals were used to train eight classifiers. It was assessed against a gold-standard Bayesian classifier developed by domain experts. It was anticipated that the Bayesian classifier, developed by experts, would exhibit comparable performance to the ML models. However, all eight classifiers outperformed it, thereby demonstrating the remarkable potential of AI in promptly identifying emerging diseases and pandemics. In a study conducted by researchers, an ensemble ML model (XGBoost) was developed to forecast the probability of developing Posttraumatic Stress Disorder 3 months after hospitalisation [79]. The model incorporated psychological and social factors, as well as information typically gathered during hospitalisation. Two studies conducted a comparison between conventional and deep learning text classifiers to determine their effectiveness in identifying altered mental status from clinical notes in the ED [80]. In addition, one of the studies employed ML models, specifically Optimal Gradient-Boosted Trees, on administrative healthcare data to predict the likelihood of suicide following a visit for parasuicide [81].

    In a study conducted, the efficacy of ML and deep learning models in predicting urinary tract infections was assessed. The models were evaluated using electronic health record data obtained from ED visits [82]. To better detect and localise fractures in x-rays researchers used U-net-based convolutional deep neural networks, training them with bootstrapping and augmenting their data to increase prediction accuracy [83]. When using the model, ED staff reduced their error rate in identifying fractures from radiographs by 47%. The diagnosis accuracy of accessible deep learning models has been demonstrated to be equal to that of experienced surgeons when applied to the wrist, ankle and hand x-rays [84]. The study showcases the potential application of deep learning in the field of screening, particularly in situations where the presence of radiologists and orthopaedic surgeons is lacking.

    7.4 Administration of an ER

    Management of the ED is a broad term for the study of issues (such as operations, logistics, contingencies, etc.) that affect the ED's efficiency. Patient care has suffered as a result of EDs being overcrowded and understaffed due to the dramatic increase in demand for their services in recent years. Seasonal and one-time events also contribute to this demand because they have been associated with health problems, both long-term and immediate, that necessitate medical attention [85-87]. Demand forecasting using conventional statistical approaches is challenging because of the significant variability and randomness of such events. AI methods have shown promise in improving ED patient load forecasting. The present study underscores the two primary advantages of employing ML and deep learning methodologies in the context of the ED. First, it enables ED staff members to accurately forecast patient volumes, thereby facilitating effective planning and allocation of medical resources. Second, it offers a comprehensive framework and tools to enhance operational efficiencies, ultimately leading to improved patient care.

    The issue of ED congestion was examined by researchers who investigated various methodologies for predicting daily arrival totals and hourly occupancy levels in real time [88]. An investigation was carried out on a data set comprising 200 weeks of everyday arrival totals, in addition to metrics related to the calendar and weather. Multiple techniques were utilised, comprising a pre-existing aggregate stochastic model, a Seasonal Autoregressive Integrated Moving Average (SARIMA) time series model, a regression approach and a MLP neural network model. The techniques were trained utilising the provided data set. The SARIMA time series model demonstrated superior forecasting performance in predicting daily arrival totals by utilising weather and calendar-related variables to establish correlations with prior daily arrival totals, as per the findings. In addition, the system exhibits the ability to forecast hourly occupancy rates with a minimal degree of inaccuracy up to 60 min in advance.

    Scholars utilised ANNs trained on historical data to improve the precision of weekly ED visit forecasts [89]. The current investigation details the effective amalgamation of a feedforward ANN and a signal-decomposition technique referred to as Ensemble Empirical Mode Decomposition. The model outperformed the ARIMA model, a conventional feed-forward neural network, and a feed-forward neural network with discrete wavelet transform decomposition in terms of performance. The above statement demonstrates the effectiveness of signal decomposition methods in enhancing generalisation capabilities and mitigating overfitting.

    The researchers employed the fundamentals of Long Short-Term Memory (LSTM) to develop a predictive model for forecasting patient visits to the ED with a lead time of up to 7 days [90]. The model was constructed after a thorough analysis of the various factors that influenced the demand for ED services. The study evaluated the efficacy of different statistical models, such as Multiple LINR, SVR, ARIMA, Generalised estimating equations, Generalised Linear Models, SARIMA, and a hybrid of ARIMA and LINR, in comparison to the LSTM model. The findings indicated that the performance of the models was inferior to that of the LSTM model. Empirical investigations carried out on patient prognosis using LSTM have exhibited encouraging outcomes [91].

    Apart from the overall patient volume, it is imperative to consider the mean duration of patients' visits to the ED. Researchers utilised ML algorithms that integrated principles of the system to generate precise wait time predictions specific to individual patients. This was done with the aim of enhancing the accuracy of ED wait time predictions [92]. The research conducted a comparative examination of a baseline LINR model and four distinct ML algorithms, specifically Stepwise Multiple LINR, SVM, ANN and Gradient Boosting Machine. The study's results indicate that the implementation of ML methods resulted in a significant decrease of 15%–20% in mean squared error (MSE) when compared to the standard model. Furthermore, the utilisation of systems yielded an additional decrease of 2% in MSE. Scholars endeavoured to enhance the quality and procedures of ED by devising a specialised ontology and a user interface propelled by ML techniques. This was documented in reference [93]. The interface utilised a multiclass support vector algorithm to aid nurses in documenting patient concerns through the implementation of top five recommendations and contextual auto-complete features. As a result of the installation, a predictable yearly reduction of 87.7% man-hours was achieved, which was attributed to a decrease in the amount of time spent typing. Additionally, the number of keystrokes required to write per presenting problem was reduced by 95%, from 11.6 keystrokes pre-implementation to 0.6 keystrokes postimplementation.

    8 ADVANTAGES OF USING AI IN EM

    Current research primarily focuses on utilising AI to predict patient triage levels, acuity and disposition as well as detect acute conditions like sepsis and myocardial infarction. Although the coverage is extensive, there are still areas that remain incomplete.

    The first identified gap pertains to the utilisation of AI in the context of patients who are in need of medical care but have not yet received it. This is a critical period during which patients may go unattended for extended periods, leading to worsening medical conditions that may necessitate immediate medical intervention. Cameras equipped with trained convolutional neural networks and embedded sensor technologies can be utilised for patient tracking and monitoring purposes. They can serve as extra observers to monitor the number of ED patients and identify individuals showing signs of potential deterioration. Data can be transmitted to a central data system for real-time analysis, enabling hospital executives to make informed decisions about operations, logistics and manpower deployment. This includes predicting trends in ED visits and alerting medical professionals to patients in critical condition amidst a busy environment. Convolutional neural network developments demonstrate the existence of these basic frameworks, which have not yet been applied to ED-related settings. The system can be integrated with a national healthcare system to provide the general public with information about ED crowds. This information can help individuals consider alternative healthcare options, such as primary healthcare facilities or 24-h clinics, for nonlife-threatening ailments. Emergency services administrators can utilise it to redirect nonemergency ambulatory occurrences to hospitals with lower patient volumes. The implementation of such systems has the potential to reduce crowds and waiting times, thus enhancing the quality of healthcare provision.

    Additional research on the integration of search engine and social media data with validated medical diagnoses can offer a comprehensive understanding of current trends and occurrences, such as emerging outbreaks. This can assist EDs in predicting staffing needs and preparing the necessary resources.

    9 LIMITATION AND CHALLENGES OF AI IN EM

    The nature of neural network models is one issue that makes it challenging for practitioners to comprehend and explain the logic behind the predictions made. The transfer and deployment of models between healthcare institutions are limited due to variations in standardisation, operating procedures and data set parameters. The values of data set parameters may vary due to differences in demographics and locale. These limitations can have a negative impact on the overall accuracy and predictive performance of the AI model, which, in turn, poses a potential risk to patients if the model is used without considering these limitations. Additional research and experimentation are necessary to determine the efficacy of the developed model. AI presents challenges in the areas of data privacy, algorithm biases and its potential impact on healthcare professionals. Therefore, it is important to address these limitations and loopholes.

    10 FUTURE PERSPECTIVE

    Examining advancements made by researchers in the domain of EM studies the authors suggest that incorporating NLP and unstructured free-text data from health records, both paper-based and electronic, has the potential to enhance triage classification and diagnosis prediction, leading to improved accuracy in overall predictions. During the transition from paper-based patient records to electronic health records in the early to mid-2000s, archived paper records were sometimes used alongside electronic records. These paper records may contain supplementary information like annotations or images that can be obtained and used to enhance models trained on text-based electronic health records.

    The increasing development of cloud-based solutions and technologies is expected to facilitate the migration of AI developments from local environments to the secure cloud. The envisioned unified training-inference-visualisation environment offers several advantages, addressing common challenges faced by early adopters. These include the management of environments, libraries, command line interfaces and the need for powerful computing hardware to train complex models. Greater user acceptance of AI in EM and other fields is achieved through increased accessibility to tools and resources, leading to wider adoption.

    Cloud-based tools can be extended and shared with medical facilities in local areas to assist physicians in diagnosing and predicting illnesses that require hospitalisation. Additionally, these tools can provide valuable data to a central hospital repository, enabling improved surveillance of outbreaks of communicable diseases and region-specific medical conditions. Early detection systems that have a broad reach can offer health authorities and EDs valuable early warnings and a more comprehensive understanding of the health status of their population. This information can assist in informed decision-making regarding the allocation of medical resources in the short, medium and long term. Additionally, it will create opportunities for a wide range of personalised healthcare solutions to address the diverse needs of the population.

    11 CONCLUSION

    The utilisation of AI in EM, specifically through ML and deep learning techniques, has witnessed a notable rise in recent times. Advancements in computational capabilities and the growing availability of data have enabled researchers to leverage AI in novel ways, resulting in improved accuracy and efficiency in the treatment of Eating Disorders. However, we firmly believe that there is significant potential for improvement in this field, which presents exciting opportunities for advancements in technology and the development of new innovations. ML and deep learning techniques have seen a rise in their application within the field of EM in recent years. Advancements in processing capabilities and data collection have enabled the use of AI to improve the accuracy and efficacy of ED therapy. This article emphasises the importance of AI in the field of EM. The article also offers explanations for various ML algorithms. This paper assesses the progress made thus far in the integration of AI and EM. This study identifies areas necessitating further research and highlights emerging opportunities. In conclusion, the integration of AI in EM shows promise by improving the accuracy and efficiency of medical care. The combination of deep learning, computer vision and NLP is anticipated to yield substantial advancements in this domain. This paper provides a comprehensive review of the current research and technology resulting from the convergence of AI and EM, while also identifying the existing gaps and future opportunities in this field. We posit that the incorporation of deep learning into this domain has the potential to yield substantial benefits, particularly when combined with computer vision and NLP.

    AUTHOR CONTRIBUTIONS

    Shivam Rajput: Conceptualisation (equal); writing—original draft (equal); Pramod Kumar Sharma: writing—original draft (supporting); Rishabha Malviya: Conceptualisation (equal); writing—review and editing; supervision (lead); project administration (lead).

    ACKNOWLEDGMENTS

    The authors have nothing to report.

      CONFLICT OF INTEREST

      The authors declare no conflict of interest.

      ETHICS STATEMENT

      The authors have nothing to report.

      INFORMED CONSENT

      The authors have nothing to report.

      DATA AVAILABILITY STATEMENT

      The authors have nothing to report.

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