Volume 33, Issue 48 p. 76
Isocyclic Compounds
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A New Mild and Rapid Deprotecting Method for Aryl Cyclohex-2-en-1-yl Ethers to Phenols.

Pascal Carato

Pascal Carato

Inst. Chim. Pharm. Albert Lespagnol, Univ. Lille 2, F-59006 Lille, Fr.

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Guillaume Laconde

Guillaume Laconde

Inst. Chim. Pharm. Albert Lespagnol, Univ. Lille 2, F-59006 Lille, Fr.

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Chehla Ladjel

Chehla Ladjel

Inst. Chim. Pharm. Albert Lespagnol, Univ. Lille 2, F-59006 Lille, Fr.

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Patrick Depreux

Patrick Depreux

Inst. Chim. Pharm. Albert Lespagnol, Univ. Lille 2, F-59006 Lille, Fr.

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Jean-Pierre Henichart

Jean-Pierre Henichart

Inst. Chim. Pharm. Albert Lespagnol, Univ. Lille 2, F-59006 Lille, Fr.

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First published: 18 May 2010

Abstract

For Abstract see ChemInform Abstract in Full Text.

ChemInform Abstract

Cyclohexyl aryl ethers (11 examples) are highly efficiently cleaved to the parent phenols using HCl in anhydrous media. The method tolerates a variety of functional groups including methoxy carbonyl.

chemical structure image

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