Heterocyclic Compounds
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ChemInform Abstract: Ruthenium-Catalyzed Oxidative Cyclization of 2-Aminobenzyl Alcohol with Ketones: Modified Friedlaender Quinoline Synthesis.
First published: 22 May 2010
Abstract
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ChemInform Abstract
A modified Friedlaender quinoline synthesis via a ruthenium-catalyzed oxidative cyclization of 2-aminobenzylalcohol (I) with ketones (II) is reported. A number of alkyl- and aryl ketones are readily cyclized with (I) affording the corresponding quinolines in good to excellent yields.
