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ChemInform Abstract: Synthesis of the First Example of a C2-C3/C2′-C3′-endo Unsaturated Pyrrolo[2,1-c][1,4]benzodiazepine Dimer.
First published: 22 May 2010
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
A versatile and efficient synthetic route to C-ring unsaturated title compounds (I) and (II) is developed. This enables the preparation of gram quantities of the clinical candidate (II) and should allow the synthesis of more structurally diverse analogues.
