ChemInform Abstract: Novel (4-Piperazin-1-ylquinolin-6-yl) Arylsulfonamides with High Affinity and Selectivity for the 5-HT₆ Receptor.

Stephen F. Moss,

Stephen F. Moss

Dep. Discovery Chem., SmithKline Beecham Pharm., New Front. Sci. Park, Harlow, Essex CM19 5AW, UK

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et al. et al.,

et al. et al.

Dep. Discovery Chem., SmithKline Beecham Pharm., New Front. Sci. Park, Harlow, Essex CM19 5AW, UK

Search for more papers by this author

Stephen F. Moss,

Stephen F. Moss

Dep. Discovery Chem., SmithKline Beecham Pharm., New Front. Sci. Park, Harlow, Essex CM19 5AW, UK

Search for more papers by this author

et al. et al.,

et al. et al.

Dep. Discovery Chem., SmithKline Beecham Pharm., New Front. Sci. Park, Harlow, Essex CM19 5AW, UK

Search for more papers by this author

First published: 22 May 2010

https://doi.org/10.1002/chin.200208166

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Abstract

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ChemInform Abstract

The discovery of the title compounds (VII) and (XII) and their binding affinities for a selection of 5-HT and dopamine subreceptors is described. Structure—activity relationships of these compounds are discussed.