ChemInform Abstract: Synthesis and Preliminary Pharmacological Evaluation of Coumestans with Different Patterns of Oxygenation.

Paulo R. R. Costa,

Paulo R. R. Costa

Lab. Quim. Bioorg., Nucl. Pesqui. Prod. Nat., Univ. Fed. Rio de Janeiro, 21941 Rio de Janeiro, Brazil

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et al. et al.,

et al. et al.

Lab. Quim. Bioorg., Nucl. Pesqui. Prod. Nat., Univ. Fed. Rio de Janeiro, 21941 Rio de Janeiro, Brazil

Search for more papers by this author

Paulo R. R. Costa,

Paulo R. R. Costa

Lab. Quim. Bioorg., Nucl. Pesqui. Prod. Nat., Univ. Fed. Rio de Janeiro, 21941 Rio de Janeiro, Brazil

Search for more papers by this author

et al. et al.,

et al. et al.

Lab. Quim. Bioorg., Nucl. Pesqui. Prod. Nat., Univ. Fed. Rio de Janeiro, 21941 Rio de Janeiro, Brazil

Search for more papers by this author

First published: 27 May 2010

https://doi.org/10.1002/chin.200118212

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Abstract

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ChemInform Abstract

Coumestans (VI) (5 examples) with different patterns of oxygenation in rings A and D are synthesized based on the Heck-type reaction of substituted chromenes (III) with organomercurials (IV) derived from resorcinols, and evaluated for their antimyotoxic activity.