ChemInform Abstract: Efficient Stereocontrolled Synthesis of 2-Benzimidazolyl- and 2-Indolyl-C-nucleosides.
Abstract
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ChemInform Abstract
The α-anomers (III) of the title compounds and the analogous β-compounds (VII) are obtained by reduction of the hemiacetals (I) and (IV) followed by Mitsunobu cyclization. The stereocontrol is observed either in the reduction or the cyclization step.