Volume 32, Issue 18
Natural Products
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ChemInform Abstract: Efficient Stereocontrolled Synthesis of 2-Benzimidazolyl- and 2-Indolyl-C-nucleosides.

Dominique Guianvarc'h

Dominique Guianvarc'h

Inst. Chim. Subst. Nat., CNRS, F-91198 Gif-sur-Yvette, Fr.

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Rachid Benhida

Rachid Benhida

Inst. Chim. Subst. Nat., CNRS, F-91198 Gif-sur-Yvette, Fr.

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Jean-Louis Fourrey

Jean-Louis Fourrey

Inst. Chim. Subst. Nat., CNRS, F-91198 Gif-sur-Yvette, Fr.

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First published: 27 May 2010

Abstract

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ChemInform Abstract

The α-anomers (III) of the title compounds and the analogous β-compounds (VII) are obtained by reduction of the hemiacetals (I) and (IV) followed by Mitsunobu cyclization. The stereocontrol is observed either in the reduction or the cyclization step.

chemical structure image

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