Volume 32, Issue 18
Heterocyclic Compounds
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ChemInform Abstract: Synthesis and Properties of 2-(4-Substituted)butyl Derivatives of Some 2,3-Dihydro-1,3-dioxo-1H-pyrrolo[3,4-c]pyridines.

H. Sladowska

H. Sladowska

Dep. Chem. Drugs, Wroclaw Univ. Med., PL-50-137 Wroclaw, Pol.

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D. Szkatula

D. Szkatula

Dep. Chem. Drugs, Wroclaw Univ. Med., PL-50-137 Wroclaw, Pol.

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B. Filipek

B. Filipek

Dep. Chem. Drugs, Wroclaw Univ. Med., PL-50-137 Wroclaw, Pol.

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D. Maciag

D. Maciag

Dep. Chem. Drugs, Wroclaw Univ. Med., PL-50-137 Wroclaw, Pol.

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J. Sapa

J. Sapa

Dep. Chem. Drugs, Wroclaw Univ. Med., PL-50-137 Wroclaw, Pol.

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M. Zygmunt

M. Zygmunt

Dep. Chem. Drugs, Wroclaw Univ. Med., PL-50-137 Wroclaw, Pol.

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First published: 27 May 2010
Citations: 4

Abstract

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ChemInform Abstract

All the title compounds (V) show strong analgesic activity, suppress spontaneous locomotor activity and prolonged barbiturate sleep. Moreover, the majority of compounds (V) significantly decreases systolic and diastolic blood pressure.

chemical structure image

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