Volume 32, Issue 18
Heterocyclic Compounds
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ChemInform Abstract: Addition of Organocopper Reagents to N-Alkylpyridinium Salts. A Flexible Access to Polysubstituted Dihydropyridines.

M.-Lluisa Bennasar

M.-Lluisa Bennasar

Lab. Quim. Org., Fac. Farm., Univ. Barcelona, E-08028 Barcelona, Spain

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Cecilia Juan

Cecilia Juan

Lab. Quim. Org., Fac. Farm., Univ. Barcelona, E-08028 Barcelona, Spain

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Joan Bosch

Joan Bosch

Lab. Quim. Org., Fac. Farm., Univ. Barcelona, E-08028 Barcelona, Spain

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First published: 27 May 2010

Abstract

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ChemInform Abstract

Addition of higher-order organocopper reagents to N-methylpyridinium salts of type (I) and quenching with trichloroacetic anhydride provides diversely substituted 1,2- and 1,4-adducts bearing electron-withdrawing groups at the 3- and 5-position.

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