Isocyclic Compounds
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ChemInform Abstract: One-Pot Synthesis of Cycloalkane Derivatives Using Allyl Phenyl Sulfone and Epoxymesylate.
First published: 30 May 2010
Abstract
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ChemInform Abstract
A facile one-pot synthesis of cycloalkane derivatives (III) and (V)/(VI) is presented, involving the reaction of lithiated allyl phenyl sulfone (II) with epoxymesylates (I) or (IV). Formation of higher cycloalkanes (-Z- > -CH2-) proceeds with excellent cis-selectivity.
