Volume 31, Issue 51
Natural Products
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ChemInform Abstract: Synthetic Studies on Brevetoxin-B. Part 3. Stereoselective Synthesis of the IJK-Ring System.

Hiroko Matsukura

Hiroko Matsukura

Inst. Phys. Chem. Res., RIKEN, Wako, Saitama 351-01, Japan

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Nobuyuki Hori

Nobuyuki Hori

Inst. Phys. Chem. Res., RIKEN, Wako, Saitama 351-01, Japan

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Goh Matsuo

Goh Matsuo

Inst. Phys. Chem. Res., RIKEN, Wako, Saitama 351-01, Japan

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Tadashi Nakata

Tadashi Nakata

Inst. Phys. Chem. Res., RIKEN, Wako, Saitama 351-01, Japan

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First published: 31 May 2010

Abstract

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ChemInform Abstract

The synthesis of title compound (X) starts from the J-ring compound (I). Further key features are the formation of the I-ring by 6-endo cyclization of the hydroxy styrylepoxide (II) and the direct introduction of the C-4-unit (VII) as the side chain.

chemical structure image

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