ChemInform Abstract: Synthetic Studies on Brevetoxin-B. Part 1. Stereoselective Synthesis of the ABC-Ring System.
Abstract
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ChemInform Abstract
The title compound (VI) is synthesized utilizing the 6-endo cyclization of the hydroxyepoxide derived from (I), a ring-closing metathesis of the diene (III) and a SmI2-induced reductive cyclization of aldehyde (V) as key steps.