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ChemInform Abstract: Synthesis and Antibacterial Activities of Novel C(3)-Aminopyrimidinyl Substituted Cephalosporins Including Against Respiratory Tract Pathogens.
First published: 31 May 2010
Abstract
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ChemInform Abstract
Cephalosporins bearing C-3-aminopyrimidinyl substituents exhibit well balanced activities against Gram-positive and Gram-negative bacteria. Thus, sixteen cephalosporins like (XI) and (XV) are prepared. They display excellent activities against major respiratory tract community pathogens such as penicillin resistant S. pneumonia, M. catarrhalis, and H. influenza.
