Volume 31, Issue 51
Natural Products
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ChemInform Abstract: Total Synthesis of Marchantinquinone.

Gloria V. Lopez

Gloria V. Lopez

Catedra Quim. Org., Fac. Quim., Univ. Rep., 11800 Montevideo, Urug.

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Enrique M. Pandolfi

Enrique M. Pandolfi

Catedra Quim. Org., Fac. Quim., Univ. Rep., 11800 Montevideo, Urug.

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Gustavo A. Seoane

Gustavo A. Seoane

Catedra Quim. Org., Fac. Quim., Univ. Rep., 11800 Montevideo, Urug.

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First published: 31 May 2010

Abstract

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ChemInform Abstract

Key steps in the synthesis of title compound (IX) are the nucleophilic SNAr-reaction of an activated benzoate derivative such as (V) with the bibenzylphenyl ether (IV) to give the diether (VI) and a macrocyclization via a Ni-mediated intramolecular coupling reaction of dichloride (VII) under optimized conditions.

chemical structure image

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