ChemInform Abstract: Syntheses of 4-[1-(2-Deoxy-β-D-ribofuranosyl)] Derivatives of 2-Substituted-5-fluoroaniline: “Cytosine Replacement” Analogues of Deoxycytidine for Evaluation as Anticancer and antihuman Immunodeficiency Virus (anti-HIV) Agents.
Abstract
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ChemInform Abstract
Screening of anticancer and anti-HIV activity of the newly prepared deoxycytidine mimic (IVa) and its precursor (IIIa) shows the lack of any biological activity.