Volume 31, Issue 51
Natural Products
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ChemInform Abstract: Syntheses of 4-[1-(2-Deoxy-β-D-ribofuranosyl)] Derivatives of 2-Substituted-5-fluoroaniline: “Cytosine Replacement” Analogues of Deoxycytidine for Evaluation as Anticancer and antihuman Immunodeficiency Virus (anti-HIV) Agents.

Zhi-Xian Wang

Zhi-Xian Wang

Fac. Pharm. Pharm. Sci., Univ. Alberta, Edmonton, Alberta T6G 2N8, Can.

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Leonard I. Wiebe

Leonard I. Wiebe

Fac. Pharm. Pharm. Sci., Univ. Alberta, Edmonton, Alberta T6G 2N8, Can.

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Erik De Clercq

Erik De Clercq

Fac. Pharm. Pharm. Sci., Univ. Alberta, Edmonton, Alberta T6G 2N8, Can.

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Jan Balzarini

Jan Balzarini

Fac. Pharm. Pharm. Sci., Univ. Alberta, Edmonton, Alberta T6G 2N8, Can.

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Edward E. Knaus

Edward E. Knaus

Fac. Pharm. Pharm. Sci., Univ. Alberta, Edmonton, Alberta T6G 2N8, Can.

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First published: 31 May 2010

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract

Screening of anticancer and anti-HIV activity of the newly prepared deoxycytidine mimic (IVa) and its precursor (IIIa) shows the lack of any biological activity.

chemical structure image

    The full text of this article hosted at iucr.org is unavailable due to technical difficulties.