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ChemInform Abstract: Synthesis of (1R,3R)-3-[2-(Aminoethyl)-2,2-dimethylcyclobutyl]methanol and (1S,3R)-(3-Amino-2,2-dimethylcyclobutyl)methanol from (+)-Nopinone.
First published: 31 May 2010
Abstract
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ChemInform Abstract
Oxime (I) and lactam (V), both derived from (+)-nopinone, are used for the preparation of the title compounds (IV) and (IX). The tetracyclic amino alcohols are of interest as “sugar” moieties of carbocyclic nucleosides.
