Preparative Organic Chemistry
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ChemInform Abstract: Bidentate Chelation-Controlled Asymmetric Synthesis of α-Hydroxy Esters Based on the Glycolate Enolate Alkylation.
First published: 08 June 2010
Abstract
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ChemInform Abstract
A new chiral auxiliary is developed and used for the asymmetric synthesis of optically active α-hydroxy esters (III). Mild reaction conditions, high stereoselectivity and the convenience of preparation and removal of the auxiliary make this method attractively.
