ChemInform Abstract: The Efficient Entry into the Tricyclic Core of Halichlorine.
Abstract
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ChemInform Abstract
The synthesis of the tricyclic core (V) of halichlorine starts from Grigg′s tricyclic isoxazolidine (II), which is easily available by tandem intramolecular Michael addition—[3 + 2] cycloaddition of the oxime of (I).