ChemInform Abstract: Synthesis of [1,4]Dioxino[2,3-c]quinolines and [1,4]Dioxepino[2,3-c]quinolines and Their 1-Sulfur Analogues.
Abstract
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ChemInform Abstract
The synthesis of dioxino- and dioxepinoquinolines (VI) and (XIIIa) with restrained conformation of the piperidine ring is described. The approach can be successfully applied to the synthesis of the 1-sulfur analogue (XIIIb) but fails for the preparation of the sulfur analogue of (VI).