ChemInform Abstract: Synthesis of the 4-Arylindole Portion of the Antitumor Agent Diazonamide and Related Studies.
Abstract
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ChemInform Abstract
Starting from the commercially available bromoarene (I), a high yielding synthesis of the CDG ring (VIII) of diazonamide is described. Furthermore, introduction of the 2-chlorosubstituent [cf. (XI) and (XIII)] is achieved, which may allow useful transformation of the skeleton.