ChemInform Abstract: Remote Chiral Induction in the Thio-Claisen Rearrangement of Bicyclic Thiolactams.
Abstract
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ChemInform Abstract
The stereochemical outcome in the thio-Claisen rearrangement taking place in bicyclic lactams is shown to be dramatically affected by remote steric effects in the oxazolidine ring of (I), (IV), and (VI).