Volume 31, Issue 12
Natural Products
Full Access

ChemInform Abstract: Use of 1,2-Dichloro 4,5-Dicyanoquinone (DDQ) for Cleavage of the 2-Naphthylmethyl (NAP) Group.

Jie Xia

Jie Xia

Dep. Biophys., Roswell Park Cancer Inst., Buffalo, NY 14263, USA

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Saeed A. Abbas

Saeed A. Abbas

Dep. Biophys., Roswell Park Cancer Inst., Buffalo, NY 14263, USA

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Robert D. Locke

Robert D. Locke

Dep. Biophys., Roswell Park Cancer Inst., Buffalo, NY 14263, USA

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Conrad F. Piskorz

Conrad F. Piskorz

Dep. Biophys., Roswell Park Cancer Inst., Buffalo, NY 14263, USA

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James L. Alderfer

James L. Alderfer

Dep. Biophys., Roswell Park Cancer Inst., Buffalo, NY 14263, USA

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Khushi L. Matta

Khushi L. Matta

Dep. Biophys., Roswell Park Cancer Inst., Buffalo, NY 14263, USA

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First published: 09 June 2010

Abstract

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ChemInform Abstract

The 2-naphthylmethyl group is useful for the protection of hydroxyl groups. It is stable to acidic conditions, but it can be removed by DDQ (conditions A).

chemical structure image

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