Heterocyclic Compounds
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ChemInform Abstract: N′-[2-(2-Thiophene)ethyl]-N′-[2′-(5-bromopyridyl)]-thiourea as a Potent Inhibitor of NNI-Resistant and Multidrug-Resistant Human Immunodeficiency Virus-1.
First published: 09 June 2010
Abstract
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ChemInform Abstract
The pyridyl ring of trovirdine is replaced by other aromatic residues. Among the newly formed compounds (V) derivative (Va) shows higher HIV-1 activity than known reference drugs (some yields not given).
