Isocyclic Compounds
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ChemInform Abstract: Medium-Sized Cyclophanes. Part 49. O-Alkylation of 8,16-Dihydroxy[2.2]metacyclophane.
First published: 09 June 2010
Abstract
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ChemInform Abstract
The selective O-monoalkylation of title compounds (I) in the presence of K2CO3 is reported. Similar reaction in the presence of Cs2CO3 or NaH affords dialkylated products (IV) in almost quantitative yield.
